Actinomycin D (10 mM)

• Catalog number
  1036-50
• Price
  Please ask
• Size
  50 ul

• Alternative_name
  Actinomycin C1, Actinomycin IV, Dactinomycin
• Description
  An antineoplastic antibiotic. Inhibits DNA-primed RNA polymerase by complexing with DNA via deoxyguanosine residues. A DNA-intercalator with growth inhibitory activity against certain leukemias and sarcomas. At higher concentrations, DNA polymerase is inhibited. Inhibits cell growth and colony formation in synchronized HeLa cells. A potent inducer of apoptosis in many cell lines (1).
• CAS Number
  50-76-0
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₆₂H₈₆N₁₂O₁₆
• Molecular Weight
  1255.5
• Cell Permeable
  No
• Purity
  >98% by TLC
• Handling
  Protect from light and moisture
• Tag Line
  An antineoplastic antibiotic
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  6 months
• MDL Number
  MFCD00005033
• PubChem CID
  2019
• PubChem CID Link
• SMILES
  CC1C(C(=O)NC(C(=O)N2CCCC2C(=O)N(CC(=O)N(C(C(=O)O1)C(C)C)C)C)C(C)C)NC(=O) C3=C4C(=C(C=C3)C)OC5=C(C(=O)C(=C(C5=N4)C(=O)NC6C(OC(=O)C(N(C(=O)CN(C(=O) C7CCCN7C(=O)C(NC6=O)C(C)C)C)C)C(C)C)C)N)C
• InChi
  InChI=1S/C62H86N12O16/c1-27(2)42-59(84)73-23-17-19-36(73)57(82)69(13)25- 38(75)71(15)48(29(5)6)61(86)88-33(11)44(55(80)65-42)67-53(78)35-22-21-31 (9)51-46(35)64-47-40(41(63)50(77)32(10)52(47)90-51)54(79)68-45-34(12)89- 62(87)49(30(7)8)72(16)39(76)26-70(14)58(83)37-20-18-24-74(37)60(85)43(28 (3)4)66-56(45)81/h21-22,27-30,33-34,36-37,42-45,48-49H,17-20,23-26,63H2, 1-16H3,(H,65,80)(H,66,81)(H,67,78)(H,68,79)
• InChi Key
  RJURFGZVJUQBHK-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Actinomycin  
• Short name
  Actinomycin D (10 mM)
• Alternative name
  Actinomycin D (10 millimeter)

Product images

Similar products