Acalabrutinib for cell activation

Acalabrutinib for cell activation is available 2 times from Biovision labs

B1193-5 | Acalabrutinib for cell activationsize: 5 mg | 178.14 USD

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B1193-25 | Acalabrutinib for cell activationsize: 25 mg | 533.25 USD

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  • Description
    Acalabrutinib (ACP-196) is an orally available, selective irreversible inhibitor of Bruton’s tyrosine kinase (BTK) with potential antineoplastic activity. It is a second generation BTK inhibitor with improved pharmacological properties with better plasma exposure, oral absorption and shorter half-life. It prevents the activation of B-cell antigen receptor (BCR) signaling pathway, thus preventing B-cell activation and BTK mediated activation of downstream survival pathways.
  • Peptide sequence
    N/A
  • CAS number
    1420477-60-6
  • Molecular weight
    465.52
  • Category
    Biochemicals
  • Other name
    (S)-4-(8-amino-3-(1-(but-2-ynoyl)pyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1-yl)-N-(pyridin-2-yl)benzamide; ACP-196
  • Molecular formula
    C₂₆H₂₃N₇O₂ 
  • Physical appearance
    Yellow Solid
  • Supplied with
    N/A
  • Is this a salt?
    No
  • Is it cell-permeable?
    Yes
  • Purification
    ≥98% by HPLC
  • Reconstitute instructions
    DMSO
  • Storage condition
    -20°C
  • Shipping condition
    gel pack
  • Maximum time for storage
    36 months
  • Storage instructions
    Protect from air and light
  • Additional description
    For cells, cell lines and tissues in culture till half confluency.
  • Gene target
  • Short name
    Acalabrutinib for activation
  • Technique
    activation
  • Alternative name
    Acalabrutinib to measure cellular activation
  • Tissue
    cell
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