ABI1 Antibody

• Catalog number
  bs-1961R
• Price
  Please ask
• Size
  0.1ml

• Long name
  ABI1 Primary Polyclonal Antibody
• Also known as
  ABI1 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  ABI1
• Specificity
  This is a highly specific antibody against ABI1.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  140-190/508
• Subcellular location
  Cytoplasm, Nucleus
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ABI1
• Gene ID number
  10006
• Swiss Prot
  Q8IZP0
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  May act in negative regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. May play a role in regulation of EGF-induced Erk pathway activation. Involved in cytoskeletal reorganization and EGFR signaling. Together with EPS8 participates in transduction of signals from Ras to Rac. In vitro, a trimeric complex of ABI1, EPS8 and SOS1 exhibits Rac specific guanine nucleotide exchange factor (GEF) activity and ABI1 seems to act as an adapter in the complex. Regulates ABL1/c-Abl-mediated phosphorylation of ENAH. Recruits WASF1 to lamellipodia and there seems to regulate WASF1 protein level. In brain, seems to regulate the dendritic outgrowth and branching as well as to determine the shape and number of synaptic contacts of developing neurons.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  E3B1; ABI-1; ABLBP4; NAP1BP; SSH3BP; SSH3BP1; Abl interactor 1; Abelson interactor 1; Abl-binding protein 4; Eps8 SH3 domain-binding protein; Eps8-binding protein; Nap1-binding protein; Spectrin SH3 domain-binding protein 1; ABI1
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  ABI1  
• Gene symbol
  ABI1
• Short name
  Anti-ABI1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  ABI1 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:11320
• Gene
  ABI1
• Long gene name
  abl interactor 1
• Synonyms gene
  • SSH3BP1
• Synonyms gene name
  • spectrin SH3 domain binding protein 1
  • abl-interactor 1
• Synonyms
  • E3B1
  • ABI-1
• GenBank acession
  • U87166
• Locus
  10p12.1
• Discovery year
  1999-05-17
• Entrez gene record
  10006
• Pubmed identfication
  • 9593709
  • 9010225
• RefSeq identity
  • NM_005470
• VEGA ID
  OTTHUMG00000017848

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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