α-naphthoflavone
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Catalog number2918-5
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PricePlease ask
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Size5 g
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Alternative_name2-phenyl-4H-naphtho[1,2-b]pyran-4-one, NSC 407011, 7,8-Benzoflavone
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DescriptionPotent and selective inhibitor of CYP19 (aromatase), CYP1A1, CYP1A2, and CYP1B1 (IC50 = 500, 60, 6, and 5 nM respectively). Can activate CYP3A4 (Kd = 7.4 µM).
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CAS Number604-59-1
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₁₉H₁₂O₂
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Molecular Weight272.3
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Purity≥98%
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SolubilitiesDMSO (~10 mg/ml) or DMF (~20 mg/ml), Ethanol (~1 mg/ml)
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HandlingProtect from air, light and moisture
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Tag LineA potent inhibitor of Cytochrome P450 enzymes (Aromatase, 1A2, 1A1, 1B1)
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life24 months
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MDL NumberMFCD00004985
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PubChem CID11790
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SMILESO=C1C2=C(C(C=CC=C3)=C3C=C2)OC(C4=CC=CC=C4)=C1
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InChiInChI=1S/C19H12O2/c20-17-12-18(14-7-2-1-3-8-14)21-19-15-9-5-4-6-13(15)10-11-16(17)19/h1-12H
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InChi KeyVFMMPHCGEFXGIP-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Short nameα-naphthoflavone
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Alternative nameα-naphthoflavone
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