A 769662, AMPK kinase activator

• Catalog number
  SIH-490-5MG
• Price
  Please ask
• Size
  5 mg

• Stock availabilitIn Stock
  In Stock
• CAS number
  844499-71-4
• Description
  AMPK kinase activator
• Molecular weight
  360,4 g/mol
• Primary research fields
  Cell Signaling
• Other name
  A-769662
• Product category
  Small Molecules
• Product type
  Activator
• Chemical formula
  C20H12N2O3S
• Origin
  Synthetic
• Purity pourcentage
  ≥99% (HPLC)
• Soluble in
  Soluble to 100 mM in DMSO and to 10 mM in ethanol
• Physical appearance
  Off-white solid
• Storage recommendations
  -20ºC
• Shipping recommendations
  Shipped Ambient
• Safety information
  Classification: Not a hazardous substance or mixture. Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
• PubChem number
  54708532
• Scientific context
  A 769662 is a potent and reversible activator of AMP-activated protein kinase (AMPK). It has been shown to inhibit fatty acid synthesis and decreases plasma glucose and triglyceride levels in vivo.
• Bibliography
  1. Sanders M.J., et al. (2007) J. Biol. Chem. 282(45): 32539–32548. 2. Göransson O., et al. (2007) J. Biol. Chem. 282(45): 32549–32560.
• Release date
  1-Oct-2014
• PubMed number
  Refer to PubMed
• Tested applications
  To be tested
• Tested reactivity
  To be tested
• Representative figure link
• Representative figure legend
  Chemical structure of A 769662 (SIH-490), a AMPK kinase activator. CAS #: 844499-71-4. Molecular Formula: C20H12N2O3S. Molecular Weight: 360.4 g/mol. Chemical structure of A 769662, a AMPK kinase activator (SIH-490). CAS # 844499-71-4. Molecular Formula: C20H12N2O3S.
• Warning information
  Non-hazardous
• Country of production
  Canada
• Total weight kg
  0.25
• Net weight g
  0.005
• Other related products

• Gene target
  769662   AMPK   kinase   activator  
• Gene symbol
  PRKAA2
• Short name
  A 769662, AMPK kinase activator
• Alternative name
  A 769662, AMPK phosphorylation catalyst activator

Gene info

• Identity
  HGNC:9377
• Gene
  PRKAA2
• Long gene name
  protein kinase AMP-activated catalytic subunit alpha 2
• Synonyms gene
  • PRKAA
• Synonyms gene name
  • protein kinase, AMP-activated, alpha 2 catalytic subunit
• Synonyms
  • AMPK
  • AMPKa2
• GenBank acession
  • BC069823
• Locus
  1p32.2
• Discovery year
  1995-12-12
• Entrez gene record
  5563
• Pubmed identfication
  • 7959015
• RefSeq identity
  • NM_006252
• VEGA ID
  OTTHUMG00000008282

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