6BIO,PDK1 kinase inhibitor

Research Area s

Cell Signaling
Category

Small Molecules
Product Type

Inhibitor
CAS No

667463-62-9
MolecularFormula

C16H10BrN3O2
Molecular Weight

356.2
Purity

≥98% (HPLC)
Solubility

Soluble to 10 mM in DMSO and to 10 mM in ethanol
Appearance

Dark red solid
Storage Temperature

-20°C
Shipping Temperature

Shipped Ambient
Description

Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.

Identity

HGNC:8809
Gene

PDK1
Long gene name

pyruvate dehydrogenase kinase 1
Synonyms gene name
- pyruvate dehydrogenase kinase, isoenzyme 1
- pyruvate dehydrogenase kinase, isozyme 1
GenBank acession
- L42450
Locus

2q31.1
Discovery year

1996-08-14
Entrez gene record

5163
Pubmed identfication
- 7499431
RefSeq identity
- NM_002610
VEGA ID

OTTHUMG00000132285