(4S)-4,9-Bis(acetyloxy)-10-[(acetyloxy)methyl]-4-ethyl-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione

• Catalog number
  B400615
• Price
  Please ask
• Size
  1 mg

• Chemical available in other sizes
  Please inquire size and price
• Stock availability
  Pending QC
• Cas number
  1304788-27-9
• Chemical s molecular weight
  520.49
• Chemical s main applications
  (4S)-4,9-Bis(acetyloxy)-10-[(acetyloxy)methyl]-4-ethyl-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione is an intermediate in the synthesis of Camptothecin analogs for the inhibition of topoisomerase I and antitumor activity.
• Chemical s category
  Chiral Reagents, Pharmaceuticals, Intermediates & Fine Chemicals,
• Chemical s formula
  C27H24N2O9
• Physical properties
  Yellow Solid
• Melting temperature
  No Data Available
• Boiling temperature
  No Data Available
• Chemical s soluble in
  DMSO, Methanol, Water
• Stability conditions
  No Data Available
• Storage
  No Data Available
• Chemical s specifications
• Description
  A methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms — CH3. In formulas, the group is often abbreviated Me. Such hydrocarbon groups occur in many organic compounds. It is a very stable group in most molecules. While the methyl group is usually part of a larger molecule, it can be found on its own in any of three forms anion, cation or radical. The anion has eight valence electrons, the radical seven and the cation six. All three forms are highly reactive and rarely observed,

• Gene target
  9-Bis   acetyloxy   acetyloxy   methyl]   4-ethyl-1H-pyrano[3   7]indolizino[1   2-b]quinoline-3   12H   dione  
• Gene symbol
  VSIR
• Short name
  (4S)-4 9-Bis(acetyloxy)-10-[(acetyloxy)methyl]-4-ethyl-1H-pyrano[3',4':6 7]indolizino[1 2-b]quinoline-3 14(4H 12H)-dione
• Alternative name
  (4S)-4,9-Bis(acetyloxy)-10-[(acetyloxy)methyl]-4-ethyl-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione

Gene info

• Identity
  HGNC:30085
• Gene
  VSIR
• Long gene name
  V-set immunoregulatory receptor
• Synonyms gene
  • C10orf54
• Synonyms gene name
  • chromosome 10 open reading frame 54
• Synonyms
  • SISP1
  • GI24
  • B7-H5
  • B7H5
  • VISTA
  • PD-1H
  • Dies1
• Synonyms name
  • stress induced secreted protein 1
  • V-domain Ig suppressor of T cell activation
  • PDCD1 homolog
• GenBank acession
  • AF193048
• Locus
  10q22.1
• Discovery year
  2005-10-06
• Entrez gene record
  64115
• Pubmed identfication
  • 12975309
  • 24691993
  • 25279955
• RefSeq identity
  • NM_022153
• Classification
  • B7 family
  • V-set domain containing
• VEGA ID
  OTTHUMG00000018426

MeSH Data

• Name
  Cloning, Molecular
• Concept
  Scope note: The insertion of recombinant DNA molecules from prokaryotic and/or eukaryotic sources into a replicating vehicle, such as a plasmid or virus vector, and the introduction of the resultant hybrid molecules into recipient cells without altering the viability of those cells.
• Tree numbers
  • E05.393.220
• Qualifiers
  drug effects, methods, radiation effects

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