Abacavir 5’-4-Chloro-6-methylpyrimidine-2,5-diamine

• Catalog number
  A105035
• Price
  Please ask
• Size
  2,5 mg

• Chemical available in other sizes
  Please inquire size and price
• Stock availability
  Please Inquire
• Cas number
  1443421-69-9
• Chemical s molecular weight
  428.88
• Chemical s main applications
  Abacavir 5’-4-Chloro-6-methylpyrimidine-2,5-diamine is a degradation product of Abacavir Sulfate (A105000). Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.
• Chemical s category
  Metabolites & Impurities, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals
• Other name
  N6-Cyclopropyl-9-((1R,4S)-4-(((2,5-diamino-6-chloropyrimidin-4-yl)oxy)methyl)cyclopent-2-en-1-yl)-9H-purine-2,6-diamine; Abacavir Related Compound D
• Chemical s formula
  C18H21ClN10O
• Physical properties
  No Data Available
• Melting temperature
  No Data Available
• Boiling temperature
  No Data Available
• Chemical s soluble in
  No Data Available
• Stability conditions
  No Data Available
• Storage
  No Data Available
• Chemical s specifications

• Gene target
  Abacavir   4-Chloro-6-methylpyrimidine-2   5-diamine  
• Gene symbol
  MIR1302-6, PIRC24, PIRC28, PIRC26, ADCP1, PIRC27, PIRC25
• Short name
  Abacavir 5’-4-Chloro-6-methylpyrimidine-2 5-diamine
• Alternative name
  Abacavir 5’-4-Chloro-6-methylpyrimidine-2,5-diamine

Gene info

• Identity
  HGNC:35298
• Gene
  MIR1302-6
• Long gene name
  microRNA 1302-6
• Synonyms gene
  • MIRN1302-6
• Synonyms
  • hsa-mir-1302-6
• Locus
  7p21.1
• Discovery year
  2008-11-03
• Entrez gene record
  100302140
• RefSeq identity
  • NR_031635
• Classification
  • MicroRNA MIR1302 family

Gene info

• Identity
  HGNC:37528
• Gene
  PIRC24
• Long gene name
  piwi-interacting RNA cluster 24
• Locus
  6
• Discovery year
  2009-11-05
• Entrez gene record
  100313810
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37532
• Gene
  PIRC28
• Long gene name
  piwi-interacting RNA cluster 28
• Locus
  6
• Discovery year
  2009-11-05
• Entrez gene record
  100313893
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37530
• Gene
  PIRC26
• Long gene name
  piwi-interacting RNA cluster 26
• Locus
  6
• Discovery year
  2009-11-05
• Entrez gene record
  100313852
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:229
• Gene
  ADCP1
• Long gene name
  adenosine deaminase complexing protein 1
• Locus
  6
• Discovery year
  1986-01-01
• Entrez gene record
  106
• Pubmed identfication
  • 279003
  • 6933468
  • 6974523

Gene info

• Identity
  HGNC:37531
• Gene
  PIRC27
• Long gene name
  piwi-interacting RNA cluster 27
• Locus
  6
• Discovery year
  2009-11-05
• Entrez gene record
  100313907
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37529
• Gene
  PIRC25
• Long gene name
  piwi-interacting RNA cluster 25
• Locus
  6
• Discovery year
  2009-11-05
• Entrez gene record
  100313851
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

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