N-Boc-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methyl-glycine

  • Catalog number
    B656785
  • Price
    Please ask
  • Size
    1 mg
  • Chemical available in other sizes
    Please inquire size and price
  • Stock availability
    Pending QC
  • Cas number
    This product doesn't have CAS Number
  • Chemical s molecular weight
    1348.75
  • Chemical s main applications
    N-Boc-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methyl-glycine is an intermediate in the synthesis of Cyclosporin AM 4N (C989410), a metabolite of Cyclosporin A (C988900). Cyclosporin A is a hydrophobic cyclic undecapeptide that is used as a potent immunosuppressive agent that has application in human organ transplantation. Cyclosporin A works by inhibiting subsets of T lymphocytes to facilitate organ transplantation.
  • Other name
    N-[(1,1-Dimethylethoxy)carbonyl]-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methyl-glycine
  • Chemical s formula
    C68H121N11O16
  • Physical properties
    White Solid
  • Melting temperature
    No Data Available
  • Boiling temperature
    No Data Available
  • Chemical s soluble in
    DCM, Methanol
  • Stability conditions
    No Data Available
  • Storage
    No Data Available
  • Description
    A methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms — CH3. In formulas, the group is often abbreviated Me. Such hydrocarbon groups occur in many organic compounds. It is a very stable group in most molecules. While the methyl group is usually part of a larger molecule, it can be found on its own in any of three forms anion, cation or radical. The anion has eight valence electrons, the radical seven and the cation six. All three forms are highly reactive and rarely observed,
  • Gene target
  • Gene symbol
    CPT1A, POM121L2, L3MBTL2, CLDN10, RPL32P1, FABP1, COX7A2, NFIA, MAS1L, ANP32E
  • Short name
    N-Boc-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S 3R 4R 6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methyl-glycine
  • Alternative name
    N-Boc homolog (mouse)-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methyl-glycine
  • Alternative to gene target
    Boc homolog (mouse), BOC and IDBG-50192 and ENSG00000144857 and 91653, protein binding, Plasma membranes, Boc and IDBG-162156 and ENSMUSG00000022687 and 117606, BOC and IDBG-632359 and ENSBTAG00000013909 and 512018
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    POM121 transmembrane nucleoporin like 2
  • Synonyms gene name
    • POM121 membrane glycoprotein-like 2 (rat)
    • POM121 membrane glycoprotein-like 2
    • POM121 transmembrane nucleoporin-like 2
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    2001-07-20
  • Entrez gene record
  • RefSeq identity
  • VEGA ID
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: The insertion of recombinant DNA molecules from prokaryotic and/or eukaryotic sources into a replicating vehicle, such as a plasmid or virus vector, and the introduction of the resultant hybrid molecules into recipient cells without altering the viability of those cells.
  • Tree numbers
    • E05.393.220
  • Qualifiers
    drug effects, methods, radiation effects
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