3 Deazaneplanocin A

3 Deazaneplanocin A is available 8 times from Biovision labs

2060-250 | 3-Deazaneplanocin Asize: 2X250 µg | 359.23 USD

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2060-1000 | 3-Deazaneplanocin Asize: 1 mg | 480.9 USD

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2060-250 | 3-Deazaneplanocin A for cell activationsize: 250 µg | 158.76 USD

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2060-1000 | 3-Deazaneplanocin A for cell activationsize: 1 mg | 391.67 USD

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2444-1000 | 3-Deazaneplanocin A hydrochloridesize: 1 mg | 434.55 USD

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2444-250 | 3-Deazaneplanocin A hydrochloridesize: 2X250 µg | 336.05 USD

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2444-250 | 3-Deazaneplanocin A hydrochloride for cell activationsize: 250 µg | 146.01 USD

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2444-1000 | 3-Deazaneplanocin A hydrochloride for cell activationsize: 1 mg | 341.85 USD

  • Catalog number
    2444-1000
  • Supplier
  • Price
    341.85 USD
  • Size
    1 mg
  • CAS number
    120964-45-6
  • Molecular weight
    298.73
  • Other name
    DZNep; NSC 617989; 5R-​(4-​amino-​1H-​imidazo[4,​5-​c]pyridin-​1-​yl)-​3-​(hydroxymethyl)-​3-​cyclopentene-​1S,​2R-​diol hydrochloride
  • Molecular formula
    C₁₂H₁₄N₄O₃. HCl
  • Physical appearance
    White to off-white solid
  • Purification
    ≥98% by HPLC
  • Reconstitute instructions
    H₂O (~5 mg/ml)
  • Storage instructions
    Protect from air and moisture
  • Additional description
    For cells, cell lines and tissues in culture till half confluency.
  • Gene target
  • Short name
    3-Deazaneplanocin A hydrochloride for activation
  • Technique
    activation
  • Alternative name
    3-Deazaneplanocin A hydrochloride to measure cellular activation
  • Tissue
    cell
Additional information
Product images
  • Formulation
    N/A
  • Peptide sequence
    N/A
  • Tagline
    A lysine methyltransferase EZH2 (KMT63) inhibitor
  • Storage Temp.
    -20°C
  • Shipping Conditions
    gel pack
  • Shelf Life
    24 months
  • Category
    Biochemicals
  • Description
    A lysine methyltransferase EZH2 (KMT63) inhibitor. DZNep is a selective inhibitor of trimethylation of lysine 27 on histone H3 (H3K27me3) and lysine 20 on histone H4 (H4K20me3). DZNep treatment of cultured human AML cells induces increased expression of the cell-cycle regulators p21, p27, and FBXO32, leading to cell cycle arrest and apoptosis.
  • Supplied with
    N/A
  • Is this a salt?
    N/A
  • Is it cell-permeable?
    Yes
  • Storage condition
    -20°C
  • Shipping condition
    gel pack
  • Maximum time for storage
    24 months
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