2 5 Dideoxyadenosine

2 5 Dideoxyadenosine is available 4 times from Biovision labs

2770-5 | 2',5'-Dideoxyadenosinesize: 5 mg | 378.56 USD

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2770-25 | 2',5'-Dideoxyadenosinesize: 25 mg | 931.84 USD

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2770-25 | 2',5'-Dideoxyadenosine for cell activationsize: 25 mg | 881.75 USD

  • Catalog number
    2770-25
  • Supplier
  • Price
    881.75 USD
  • Size
    25 mg
  • Additional description
    For cells, cell lines and tissues in culture till half confluency.
  • Gene target
  • Short name
    2',5'-Dideoxyadenosine for activation
  • Alternative name
    2',5'-Dideoxyadenosine to measure cellular activation
MeSH Data
  • Name
  • Concept
    Registry number:4Q86AH641A
    Scope note:A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. The compound is an inhibitor of HIV replication, acting as a chain-terminator of viral DNA by binding to reverse transcriptase. Its principal side effect is nephrotoxicity. In vivo, dideoxyadenosine is rapidly metabolized to DIDANOSINE (ddI) by enzymatic deamination; ddI is then converted to dideoxyinosine monophosphate and ultimately to dideoxyadenosine triphosphate, the putative active metabolite.
    CASN1 number:Adenosine, 2',3'-dideoxy-
  • Tree numbers
    • D03.633.100.759.590.138.325.105
    • D13.570.230.229.105
    • D13.570.230.500.105
    • D13.570.583.138.325.105
Additional information
Product images

2770-5 | 2',5'-Dideoxyadenosine for cell activationsize: 5 mg | 279.55 USD

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  • Alternate Name/Synonyms
    2',5'-Dideoxy-D-adenosine; 2’,5’-DDA
  • Appearance
    White to off-white solid
  • Formulation
    N/A
  • CAS Number
    6698-26-6
  • Peptide sequence
    N/A
  • Molecular Formula
    C₁₀H₁₃N₅O₂
  • Molecular Weight
    235.25
  • Purity
    ≥98% by HPLC
  • Solubility/Reconstitution Instructions
    H₂O (~20 mg/ml, warming) or DMSO (~ 30 mg/ml)
  • Handling
    Protect from light and moisture
  • Tagline
    An adenylate cyclase inhibitor
  • Storage Temp.
    -20°C
  • Shipping Conditions
    Gel Pack
  • Shelf Life
    36 months
  • MDL Number
    MFCD00210904
  • PubChem CID
    65166
  • Category
    Biochemicals
  • Description
    2’, 5’- Dideoxyadenosine is a cell-permeable inhibitor of adenylate cyclase (IC₅₀ = 2.7 µM). Inhibits growth and causes cell differentiation (1.5 µM) in K562 cells.
  • CAS number
    6698-26-6
  • Molecular weight
    235.25
  • Other name
    2',5'-Dideoxy-D-adenosine; 2’,5’-DDA
  • Molecular formula
    C₁₀H₁₃N₅O₂
  • Physical appearance
    White to off-white solid
  • Supplied with
    N/A
  • Is this a salt?
    No
  • Is it cell-permeable?
    Y
  • Purification
    ≥98% by HPLC
  • Reconstitute instructions
    H₂O (~20 mg/ml, warming) or DMSO (~ 30 mg/ml)
  • Storage condition
    -20°C
  • Shipping condition
    Gel Pack
  • Maximum time for storage
    36 months
  • Storage instructions
    Protect from light and moisture
  • Technique
    activation
  • Tissue
    cell
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