1.65ml Natural conical tube with screw cap, 500/bag
1.65ml Natural conical tube with screw cap, 500/bag is available 1 time from Biobasics labs
TC151-N | 1.65ml Natural conical tube with screw cap, 500/bagsize: 1PK | 175.48 USD
- Catalog numberTC151-N
- Price175.48 USD
- PubMedThus, BAG2 promotes mutant p53 accumulation and gain-of-function in tumor growth, metastasis and chemoresistance.this data correlate BAG2 to PINK1 for the first time, strengthening the important role of BAG2 in Parkinson disease -related neurodegeneration.we measured the binding of human Hsp72 (HSPA1A) to BAG1, BAG2, BAG3, and the unrelated NEF Hsp105. These studies revealed a clear hierarchy of affinities: BAG3 > BAG1 > Hsp105 >> BAG2.BAG2 binds to the carboxyl terminus of Hsp70-interacting protein (CHIP) and provides a cochaperone-dependent regulatory mechanism for preventing unregulated ubiquitylation of misfolded proteins by CHIPBAG2 was directly phosphorylated at serine 20 in vitro by MAPKAPK2 and MAPKAP2 is also required for phosphorylation of BAG2 in vivo.The activity of BAG-2 resembles that of the previously characterized Hsc70 cochaperone and CHIP inhibitor HspBP1.NF-kappaB-mediated modulation of BAG2 expression regulates the shift between the neurotrophic and neurotoxic effects of Abeta1-42.repression of BAG2 expression or BAG2 activity by cold-sensitive pathways, as modeled in undifferentiated and differentiated cells, respectively, may be a causal factor in the accumulation of cytotoxic hyperphosphorylated tau protein.
- Gene ontology - Biological process
- Gene ontology - Cellular component
- Gene ontology - Molecular function
- Entrez Gene
- Availability and orderingPlease contact Gentaur/Genprice team to check availability and to request a quote
- NoteThis product is produced in USA according to the goods manufacturing practices and is designed specifically for Research Use Only.
- Gene target
- Short name1.65ml Natural conical tube with screw cap, 500/bag
- Alternative name1.65ml Natural conical tube including screw cap, 500/bag
- Alternative techniquetubes