14 3 3 sigma Antibody ALEXA FLUOR

14 3 3 sigma Antibody ALEXA FLUOR is available 5 times from Bioss primary conjugated antibodies. alexa fluor labs

bs-12422R-A350 | 14-3-3 sigma Antibody, ALEXA FLUOR 350size: 100ul | 379.04 USD

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bs-12422R-A488 | 14-3-3 sigma Antibody, ALEXA FLUOR 488size: 100ul | 379.04 USD

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bs-12422R-A555 | 14-3-3 sigma Antibody, ALEXA FLUOR 555size: 100ul | 379.04 USD

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bs-12422R-A594 | 14-3-3 sigma Antibody, ALEXA FLUOR 594size: 100ul | 379.04 USD

  • Long name
    14-3-3 sigma Polyclonal Antibody, ALEXA FLUOR 594 Conjugated
  • Also known as
    Anti-14-3-3 sigma PAb ALEXA FLUOR 594
  • Conjugated with
    ALEXA FLUOR® 594
  • Excitation emission
    590nm/617nm
  • Properties
    For facs or microscopy Alexa 1 conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Conjugation
    Alexa Fluor,ALEXA FLUOR® 594
  • Conjugated
    Alexa conjugate 1
  • French translation
    anticorps
  • Label
    ALEXA FLUOR 594
  • Alternative name
    14-3-3 sigma (Antibody to), ALEXA FLUOR 594
1. Gene info
  • Identity
  • Gene
  • Long gene name
    tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
  • Synonyms gene name
    • tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
    • protein, theta
  • Synonyms
  • Synonyms name
  • GenBank acession
  • Locus
  • Discovery year
    1999-08-20
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • 14-3-3 phospho-serine/phospho-threonine binding proteins
  • Havana BLAST/BLAT
2. Gene info
MeSH Data
  • Name
  • Concept
    Scope note:Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
Additional information
Product images

bs-12422R-A647 | 14-3-3 sigma Antibody, ALEXA FLUOR 647size: 100ul | 379.04 USD

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  • Category
    Conjugated Primary Antibodies
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    14-3-3 sigma
  • Specificity
    This is a highly specific antibody against 14-3-3 sigma.
  • Modification
    Unmodified
  • Modification Site
    None
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Concentration
    1ug per 1ul
  • Source
    This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human 14-3-3 sigma
  • Gene ID Number
    2810
  • Tested applications
    IF(IHC-P)
  • Recommended dilutions
    IF(IHC-P)(1:50-200)
  • Crossreactivity
    Human, Mouse, Rat
  • Cross-reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the antigen
    14-3-3 proteins regulate many cellular processes relevant to cancer biology, notably apoptosis, mitogenic signaling and cell-cycle checkpoints. Seven isoforms, denoted 14-3-3 b, g, e, z, h, q and s, comprise this family of signaling intermediates. 14-3-3 s, also known as SFN, stratifin, HME1 or YWHAS, is a secreted adaptor protein that is involved in regulating both general and specific signaling pathways. Expressed predominately in stratified squamous keratinising epithelium, 14-3-3 s is able to bind and modify the activity of a large number of proteins, such as KRT17 (Keratin 17), through recognition of a phosphothreonine or phosphoserine motif. When bound to Keratin 17, for example, 14-3-3 s acts to stimulate the Akt/mTOR signaling pathway by upregulating protein synthesis and cell growth. 14-3-3 s also functions to positively mediate IGF-I-induced cell cycle progression and can bind to a variety of translation initiation factors, thus controlling mitotic translation. In response to tumor growth, 14-3-3 s positively regulates the tumor suppressor p53 and increases the rate of p53-regulated inhibition of G2/M cell cycle progression. Multiple isoforms of 14-3-3 s exist due to alternative splicing events.
  • Purification
    Purified by Protein A.
  • Storage conditions
    Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
  • Synonyms
    14 3 3 protein sigma; 14-3-3 protein sigma; 1433S_HUMAN; Epithelial cell marker protein 1; Er; HME 1; HME1; MGC143283; Mkrn3; Mme1; OTTHUMP00000004242; RP23 137L22.11; SFN; SFN protein; Stratin; YWHAS.
  • Gene target
  • Short name
    14-3-3 sigma Antibody,
  • Technique
    Antibody
  • Alternative technique
    antibodies
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