cis-1-[2-[(Acetyloxy)methyl]-1,3-oxathiolan-5-yl]-5-fluoro-2,4(1H,3H)-pyrimidinedione

• Catalog number
  A591345
• Price
  Please ask
• Size
  1 mg

• Chemical available in other sizes
  Please inquire size and price
• Stock availability
  Please Inquire
• Cas number
  144963-94-0
• Chemical s molecular weight
  290.27
• Chemical s main applications
  cis-1-[2-[(Acetyloxy)methyl]-1,3-oxathiolan-5-yl]-5-fluoro-2,4(1H,3H)-pyrimidinedione is an impurity in the synthesis of Labelled Emtricitabine which is a reverse transcriptase inhibitor. It is an effective antiviral agent against HIV, HBV, and other viruses replicating in a similar manner. A nucleoside analog structurally related to Lamivudine (L172500).
• Chemical s formula
  C10H11FN2O5S
• Physical properties
  Off-White Solid
• Melting temperature
  No Data Available
• Boiling temperature
  No Data Available
• Chemical s soluble in
  Dimethylsulfoxide, Methanol
• Stability conditions
  No Data Available
• Storage
  No Data Available
• Chemical s specifications
• Description
  A methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms — CH3. In formulas, the group is often abbreviated Me. Such hydrocarbon groups occur in many organic compounds. It is a very stable group in most molecules. While the methyl group is usually part of a larger molecule, it can be found on its own in any of three forms anion, cation or radical. The anion has eight valence electrons, the radical seven and the cation six. All three forms are highly reactive and rarely observed,

• Gene target
  cis-1   Acetyloxy   methyl]   3-oxathiolan-5-yl]   5-fluoro-2   pyrimidinedione  
• Gene symbol
  MIR1302-5, PIRC23, PIRC22, PIRC20, PIRC21, HTR6, IGHV2OR16-5, IGKV3OR2-5, SNORD116-5, TGFB1I1
• Short name
  cis-1-[2-[(Acetyloxy)methyl]-1 3-oxathiolan-5-yl]-5-fluoro-2 4(1H 3H)-pyrimidinedione
• Alternative name
  cis-1-[2-[(Acetyloxy)methyl]-1,3-oxathiolan-5-yl]-5-fluoro-2,4(1H,3H)-pyrimidinedione

Gene info

• Identity
  HGNC:35297
• Gene
  MIR1302-5
• Long gene name
  microRNA 1302-5
• Synonyms gene
  • MIRN1302-5
• Synonyms
  • hsa-mir-1302-5
• Locus
  20q13.13
• Discovery year
  2008-11-03
• Entrez gene record
  100302146
• RefSeq identity
  • NR_031634
• Classification
  • MicroRNA MIR1302 family

Gene info

• Identity
  HGNC:37527
• Gene
  PIRC23
• Long gene name
  piwi-interacting RNA cluster 23
• Locus
  5
• Discovery year
  2009-11-05
• Entrez gene record
  100313786
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37526
• Gene
  PIRC22
• Long gene name
  piwi-interacting RNA cluster 22
• Locus
  5
• Discovery year
  2009-11-05
• Entrez gene record
  100313850
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37524
• Gene
  PIRC20
• Long gene name
  piwi-interacting RNA cluster 20
• Locus
  5
• Discovery year
  2009-11-05
• Entrez gene record
  100313785
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37525
• Gene
  PIRC21
• Long gene name
  piwi-interacting RNA cluster 21
• Locus
  5
• Discovery year
  2009-11-05
• Entrez gene record
  100313916
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:5301
• Gene
  HTR6
• Long gene name
  5-hydroxytryptamine receptor 6
• Synonyms gene name
  • 5-hydroxytryptamine (serotonin) receptor 6
  • 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
• Synonyms
  • 5-HT6
  • 5-HT6R
• GenBank acession
  • L41147
• Locus
  1p36.13
• Discovery year
  1997-12-11
• Entrez gene record
  3362
• Pubmed identfication
  • 8522988
• RefSeq identity
  • NM_000871
• Classification
  • 5-hydroxytryptamine receptors, G protein-coupled
• VEGA ID
  OTTHUMG00000002713

Gene info

• Identity
  HGNC:5579
• Gene
  IGHV2OR16-5
• Long gene name
  immunoglobulin heavy variable 2/OR16-5 (non-functional)
• Synonyms gene name
  • immunoglobulin heavy variable 2/OR16-5
• Synonyms
  • IGHV2/OR16-5
• GenBank acession
  • L25544
• Locus
  16p11.2
• Discovery year
  2000-04-17
• Entrez gene record
  100129631
• Classification
  • Immunoglobulin heavy (IGH) orphons
• VEGA ID
  OTTHUMG00000152881

Gene info

• Identity
  HGNC:5832
• Gene
  IGKV3OR2-5
• Long gene name
  immunoglobulin kappa variable 3/OR2-5 (pseudogene)
• Synonyms gene name
  • immunoglobulin kappa variable 3/OR2-5
  • immunoglobulin kappa variable 3/OR2-5 pseudogene
• Synonyms
  • IGKV3/OR2-5
• GenBank acession
  • X51882
• Locus
  2q11.2
• Discovery year
  2000-04-18
• Entrez gene record
  28854
• Classification
  • Immunoglobulin kappa (IGK) orphons
• VEGA ID
  OTTHUMG00000184519

Gene info

• Identity
  HGNC:33071
• Gene
  SNORD116-5
• Long gene name
  small nucleolar RNA, C/D box 116-5
• Synonyms
  • HBII-85-5
• GenBank acession
  • AF250841
• Locus
  15q11.2
• Discovery year
  2007-02-15
• Entrez gene record
  100033417
• Pubmed identfication
  • 11106375
  • 11726556
• RefSeq identity
  • NR_003320
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:11767
• Gene
  TGFB1I1
• Long gene name
  transforming growth factor beta 1 induced transcript 1
• Synonyms
  • Hic-5
  • TSC-5
  • ARA55
  • HIC-5
• Synonyms name
  • hydrogen peroxide-inducible clone-5
• GenBank acession
  • AB007836
• Locus
  16p11.2
• Discovery year
  1998-03-23
• Entrez gene record
  7041
• Pubmed identfication
  • 9422762
  • 10075738
• Classification
  • LIM domain containing
• VEGA ID
  OTTHUMG00000132467

MeSH Data

• Name
  Cloning, Molecular
• Concept
  Scope note: The insertion of recombinant DNA molecules from prokaryotic and/or eukaryotic sources into a replicating vehicle, such as a plasmid or virus vector, and the introduction of the resultant hybrid molecules into recipient cells without altering the viability of those cells.
• Tree numbers
  • E05.393.220
• Qualifiers
  drug effects, methods, radiation effects

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