10058-F4

• Catalog number
  2739-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  5-[(4-Ethylphenyl)methylene]-2-thioxo-4-thiazolidinone
• Description
  10058-F4 is a c-Myc inhibitor that inhibits the c-Myc-Max associationn and function. It prevents the growth of fibroblasts in a c-Myc-dependent manner. Downregulates human telomerase reverse transcriptase and enhances chemosensitivity in human hepatocellular carcinoma cells. Induces cell cycle arrest, apoptosis and myeloid differentiation in human acute myeloid leukemia. 10058-F4 inhibits the MYCN/Max interaction leading to cell cycle arrest, apoptosis and neuronal differentiation in MYCN-amplified neuroblastoma cells.
• CAS Number
  403811-55-2
• Structure Available
  Y
• Salt Form
  No
• Molecular Formula
  C₁₂H₁₁NOS₂
• Molecular Weight
  249.35
• Cell Permeable
  Yes
• Purity
  ≥98% by TLC
• Solubilities
  DMSO (60 mg/ml) or EtOH (20 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A c-Myc inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  Gel Pack
• Shelf Life
  36 months
• MDL Number
  MFCD00758517
• PubChem CID
  1271002
• PubChem CID Link
• SMILES
  CCC1=CC=C(C=C1)C=C2C(=O)NC(=S)S2
• InChi
  InChI=1S/C12H11NOS2/c1-2-8-3-5-9(6-4-8)7-10-11(14)13-12(15)16-10/h3-7H,2H2,1H3,(H,13,14,15)/b10-7+
• InChi Key
  SVXDHPADAXBMFB-JXMROGBWSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  10058-F4  
• Short name
  10058-F4
• Alternative name
  10058-F4

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