2,6,7,8,9,10-Hexahydro-10-[(2-methylphenyl)methyl]-7-(phenylmethyl)-imidazo[1,2-a]pyrido[4,3-d]pyrimidin-5(3H)-one

  • Catalog number
    H291055
  • Price
    Please ask
  • Size
    5 mg
  • Chemical available in other sizes
    Please inquire size and price
  • Stock availability
    Please Inquire
  • Cas number
    41276-02-2
  • Chemical s molecular weight
    386.49
  • Chemical s main applications
    2,6,7,8,9,10-Hexahydro-10-[(2-methylphenyl)methyl]-7-(phenylmethyl)-imidazo[1,2-a]pyrido[4,3-d]pyrimidin-5(3H)-one is a small molecule TRAIL gene induction by normal and tumor cells as an anticancer therapy. The compound identified as NSC 350625 was assigned the structure above for many years. The compound is correctly characterized as B285480. The resolution of this issue was recently highlighted in Chemical and Engeneering News 92(23) 32 (2014).
  • Chemical s category
    Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
  • Other name
    NSC 350625; TIC10; ONC201
  • Chemical s formula
    C24H26N4O
  • Physical properties
    No Data Available
  • Melting temperature
    No Data Available
  • Boiling temperature
    No Data Available
  • Chemical s soluble in
    No Data Available
  • Stability conditions
    No Data Available
  • Storage
    No Data Available
  • Description
    A methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms — CH3. In formulas, the group is often abbreviated Me. Such hydrocarbon groups occur in many organic compounds. It is a very stable group in most molecules. While the methyl group is usually part of a larger molecule, it can be found on its own in any of three forms anion, cation or radical. The anion has eight valence electrons, the radical seven and the cation six. All three forms are highly reactive and rarely observed,
  • Gene target
  • Gene symbol
    PIRC49, SNORD115-10, SNORD116-10, IGHV3OR16-10, IGKV2OR2-10, ERVK-10
  • Short name
    2 6 7 8 9 10-Hexahydro-10-[(2-methylphenyl)methyl]-7-(phenylmethyl)-imidazo[1 2-a]pyrido[4 3-d]pyrimidin-5(3H)-one
  • Alternative name
    2,6,7,8,9,10-Hexahydro-10-[(2-methylphenyl)methyl]-7-(phenylmethyl)-imidazo[1,2-a]pyrido[4,3-d]pyrimidin-5(3H)-one
Gene info
  • Identity
  • Gene
  • Long gene name
    piwi-interacting RNA cluster 49
  • Locus
    10
  • Discovery year
    2009-11-05
  • Entrez gene record
  • Pubmed identfication
  • Classification
    • Piwi-interacting RNA clusters
Gene info
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    immunoglobulin heavy variable 3/OR16-10 (non-functional)
  • Synonyms gene name
    • immunoglobulin heavy variable 3/OR16-10
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    2000-04-17
  • Entrez gene record
  • Classification
    • Immunoglobulin heavy (IGH) orphons
  • VEGA ID
Gene info
  • Identity
  • Gene
  • Long gene name
    immunoglobulin kappa variable 2/OR2-10 (pseudogene)
  • Synonyms gene name
    • immunoglobulin kappa variable 2/OR2-10
    • immunoglobulin kappa variable 2/OR2-10 pseudogene
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    2000-04-18
  • Entrez gene record
  • RefSeq identity
  • Classification
    • Immunoglobulin kappa (IGK) orphons
Gene info
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