MRP8/14 Activated Macrophages (human) - Clone 27E10

• Catalog number
  T-1023.0100
• Price
  Please ask
• Size
  100ug

• Synonym
  S100A8/S100A9, L-1 Inflammatory Protein, Calprotectin
• StorageTemperature
  +5 ± 3 °C
• HOST
  Mouse
• Clone
  270000000000
• Format
  Purified, Lyophilized
• Species Crossreactivity
  human
• Application
  IHC, ELISA
• Conjugate
  NA
• Top Categories
  Antibodies
• Keywords
  Monoclonal; primary antibody
• Additonal Description
  27E10 is a unique monoclonal antibody that recognizes an epitope on the MRP8/14 heterocomplex that is not exposed on the individual subunits MRP8 or MRP14. It is ideally suited for the detection of early inflammatory macrophages and therefore for the classification of acute stage inflammation in tissue sections and in smears, the characterization of tumorous tissues and the in vitro monitoring of peripheral blood cell cultures. The MRP8/14 specific ELISA has shown unprecedented advantages in the early assessment of acute inflammatory conditions like transplant rejection. Application: IHC (f, p), Serology, ELISA
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

• Gene target
  MRP8/14   Activated   Macrophages   27E10  
• Gene symbol
  ABCC11, ABCC8, S100A8
• Short name
  MRP8/14 Activated Macrophages ( ) - Clone 27E10
• Isotype
  IgG1
• Species
  Human, Humans
• Alternative name
  MRP8/14 Activated Macrophages (H. sapiens) - clonality 27E10
• Clone name
  27E10

Gene info

• Identity
  HGNC:14639
• Gene
  ABCC11
• Long gene name
  ATP binding cassette subfamily C member 11
• Synonyms gene name
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 11
• Synonyms
  • MRP8
• GenBank acession
  • AF367202
• Locus
  16q12.1
• Discovery year
  2001-06-01
• Entrez gene record
  85320
• Pubmed identfication
  • 11483364
  • 11435397
• RefSeq identity
  • NM_032583
• Classification
  • ATP binding cassette subfamily C
• VEGA ID
  OTTHUMG00000133146

Gene info

• Identity
  HGNC:59
• Gene
  ABCC8
• Long gene name
  ATP binding cassette subfamily C member 8
• Synonyms gene
  • SUR
  • HRINS
• Synonyms gene name
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 8
• Synonyms
  • HI
  • PHHI
  • SUR1
  • MRP8
  • ABC36
  • HHF1
  • TNDM2
• Synonyms name
  • sulfonylurea receptor (hyperinsulinemia)
• GenBank acession
  • L78207
• Locus
  11p15.1
• Discovery year
  1995-01-10
• Entrez gene record
  6833
• Pubmed identfication
  • 7920639
  • 7716548
• RefSeq identity
  • NM_000352
• Classification
  • ATP binding cassette subfamily C
• VEGA ID
  OTTHUMG00000166316
• Locus Specific Databases
  • LRG_790

Gene info

• Identity
  HGNC:10498
• Gene
  S100A8
• Long gene name
  S100 calcium binding protein A8
• Synonyms gene
  • CAGA
  • CFAG
• Synonyms gene name
  • calgranulin A
  • cystic fibrosis antigen
• Synonyms
  • P8
  • MRP8
  • MRP-8
  • 60B8AG
  • CGLA
  • S100-A8
• Synonyms name
  • Migration inhibitory factor-related protein 8
  • Calprotectin L1L subunit
  • Leukocyte L1 complex light chain
• GenBank acession
  • BC005928
• Locus
  1q21.3
• Discovery year
  1989-05-19
• Entrez gene record
  6279
• RefSeq identity
  • NM_002964
• Classification
  • S100 calcium binding proteins
  • EF-hand domain containing
• VEGA ID
  OTTHUMG00000013124

Similar products