Sheep anti KSHV/HHV8 (cyclin)
-
Catalog number
F105P
-
Price
Please ask
-
Size
250 μg
-
-
Category
Primary Antibodies
-
Long description
Human herpervirus-8 (HHV-8) cyclin is a component of the HHV-8 virus particle. HHV8 has been found to be associated with three different diseases observed in AIDS patients; kaposi's sarcoma, primary effusion lymphoma (which is a rare type of non-Hodgkin lymphoma affecting the body cavities) and multicentric Castleman's disease. To date there is much evidence to support a direct role for HHV8 in kaposi's sarcoma.
-
Antibody come from
Inclusion Bodies from E. Coli expressing his-tagged full length human cyclin G2 protein.
-
Other description
Provided as solution in phosphate buffered saline with 0.08% sodium azide. Ammonium Sulfate Precipitation
-
Clone
Polyclonal
-
Antigen antibody binding interaction
Sheep anti KSHV/HHV8 (cyclin) Antibody
-
Antibody is raised in
Sheep
-
Antibody s reacts with
see techfile
-
Antibody s reacts with these species
This antibody doesn't cross react with other species
-
Antibody s specificity
No Data Available
-
Application
Immunoprecipitation
-
Antibody s suited for
Applications: Immunoblotting 1-5 ug/ml. Immunoprecipitation 10-20 ug/ml.
-
Storage
-20ºC
-
Relevant references
Carbone, A., et al. 'Proliferation in HHV-8-positive primary effusion lymphomas is associated with expression of HHV-8 cyclin but independent of p27(kip1).' Am. J. Pathol. 2000, 156, 1209-1215_x000B__x000B_Product Specific References:_x000B__x000B_1. Godfrey, A., et al. 'Inhibiting primary effusion lymphoma by leniviral vectors encoding short hairpin RNA.' Blood, 2005, 105, 2510-2518._x000B__x000B_2. Sugaya, M., et al. 'Lymphatic dysfunction in transgenic mice expressing KSHV k-cyclin under the control of the VEGFR-3 promoter.' Blood, 2005, 105, 2356-2363._x000B__x000B_3. Jarviluoma, A., et al. 'KSHV viral cyclin binds to p27KIP1 in primary effusion lymphomas.' Blood, 2004, 104, 3349-3354.
-
Protein number
see ncbi
-
Warnings
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
-
-
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
-
Gene target
-
Short name
anti KSHV/HHV8 (cyclin)
-
Technique
anti, antibody to
-
Host
Sheep
-
Isotype
not specified
-
Label
unlabeled
-
Species
Sheep, The sheep (Ovis aries) ELISAs are detecting sheep proteins and antigens. Some epitopes will also recognize goat proteins. Sheep and goats are also used to produce polyclonals. An adult female sheep is referred to as a ewe a male as a ram, a castrated male as a wether, and a younger sheep as a lamb. Sheeps
-
Alternative name
ovine antibody to KSHV/HHV8 (cyclin)
-
Alternative technique
antibodies
-
Virus
hhv8, kshv
-
MeSH Data
-
Name
-
Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
Similar products