APP/Protease Nexin II

Alternative Names

amyloid beta A4 protein precursor, isoform, amyloid beta (A4) precursor protein, Alzheimer disease, peptidase nexin-II
Product Type

Monoclonal Antibody
NCBI Number

NP_000475
Concentration

1mg/ml
Formulation

Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol.
Immunogen

Recombinant human APP (18-289aa) purified from E. coli
Applications

ELISA,WB,ICC/IF,FACS
Reacts With

Human
Clone

J4H9
Usage

The antibody has been tested by ELISA, Western blot, ICC/IF and FACS analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
Antigen Species

Human
UniProt No

P05067
Gene Category

Neuroscience
Conjugation

Unconjugated
Clonality

Monoclonal
Ab Purification Comment

By protein-G affinity chromatography
Storage and shipping

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Data sheet
Note

This product is available in other size, please contact us for more details

Gene target

APP/Protease Nexin
Gene symbol

APP-DT, APP, PABPC4, NAE1
Short name

APP/Protease Nexin II
Host

Mouse
Isotype

IgG2b kappa
Alternative name

amyloid beta (A4) precursor protein/Protease Nexin II
Alternative to gene target

amyloid beta (A4) precursor protein, AAA and ABETA and ABPP and AD1 and APPI and CTFgamma and CVAP and PN-II and PN2, APP and IDBG-1100 and ENSG00000142192 and 351, growth factor receptor binding, nuclei, App and IDBG-172954 and ENSMUSG00000022892 and 11820, APP and IDBG-630293 and ENSBTAG00000017753 and 280722

Identity

HGNC:620
Gene

APP
Long gene name

amyloid beta precursor protein
Synonyms gene
- AD1
Synonyms gene name
- Alzheimer disease
- amyloid beta (A4) precursor protein
Synonyms
- alpha-sAPP
Synonyms name
- peptidase nexin-II
GenBank acession
- M15533
Locus

21q21.3
Discovery year

1986-01-01
Entrez gene record

351
Pubmed identfication
- 1679289
RefSeq identity
- NM_000484
Classification
- Receptor ligands
VEGA ID

OTTHUMG00000078438
Locus Specific Databases
- Alzheimer Disease & Frontotemporal Dementia Mutation Database

Identity

HGNC:8557
Gene

PABPC4
Long gene name

poly(A) binding protein cytoplasmic 4
Synonyms gene name
- poly(A)-binding protein, cytoplasmic 4 (inducible form)
- poly(A) binding protein, cytoplasmic 4 (inducible form)
Synonyms
- iPABP
- APP-1
Synonyms name
- activated-platelet protein 1
- Inducible poly(A)-binding protein
GenBank acession
- U33818
Locus

1p34.3
Discovery year

1999-12-17
Entrez gene record

8761
Pubmed identfication
- 10543404
RefSeq identity
- NM_001135653
Classification
- RNA binding motif containing
- Small nucleolar RNA protein coding host genes
VEGA ID

OTTHUMG00000009097