SPIB Antibody

• Catalog number
  N1035-100UG
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
• Form
  Purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  SPIB
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 4-8ug/ml
• Notes
  Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.
• Added buffer
  1X Phosphate Buffered Saline (PBS), pH 7.4
• Intented use
  This SPIB antibodyis to be used only for research purposes and not for diagnostics..
• Gene ID
  6689
• Purity
  Purified by protein A Affinity Chromatography
• Description
  SPIB is a transcription factor in the Ets family. It is found in lymphoid cells and not in monocytes or myeloid cells. SPIB is a regulator of pDC development via its interaction with ID2, E2-2 and BCL2-A1. It promotes E2-2 activity and suppresses Id2 expression to enhance pDC development. It also promotes pDC survival by activation of the antiapoptotic gene BCL2-A1.
• Immunogen
  A recombinant protein fragment from the C-terminal half of SPIB was used as the immunogen for this antibody.
• Storage
  Aliquot and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  SPIB  
• Gene symbol
  SPIB
• Short name
  Anti-SPIB
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to SPIB
• Alternative technique
  antibodies
• Alternative to gene target
  Spi-B transcription factor (Spi-1/PU.1 related), SPI-B, SPIB and IDBG-729211 and ENSG00000269404 and 6689, sequence-specific DNA binding, nuclei

Gene info

• Identity
  HGNC:11242
• Gene
  SPIB
• Long gene name
  Spi-B transcription factor
• Synonyms gene name
  • Spi-B transcription factor (Spi-1/PU.1 related)
• Synonyms
  • SPI-B
• Locus
  19q13.33
• Discovery year
  1994-12-15
• Entrez gene record
  6689
• Pubmed identfication
  • 1406622
• RefSeq identity
  • NM_003121
• Classification
  • ETS transcription factor family
• VEGA ID
  OTTHUMG00000183039

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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