LAMC2 Antibody

  • Catalog number
  • Price
    Please ask
  • Size
  • Category
  • Concentration
    0.5mg/ml if reconstituted with 0.2ml sterile DI water
  • Form
    Antigen affinity purified
  • Conjugation
  • Clone
    Polyclonal antibody
  • Recognised antigen
  • Host animal
    Rabbit (Oryctolagus cuniculus)
  • Clonality
    Polyclonal (rabbit origin)
  • Species reactivity
    Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
  • Tested applications
    WB, IHC-P
  • Recommended dilutions
    Western blot: 0.5-1ug/ml,IHC (Paraffin): 0.5-1ug/ml
  • Notes
    The stated application concentrations are suggested starting amounts. Titration of the LAMC2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
  • Intented use
    This LAMC2 antibodyis to be used only for research purposes and not for diagnostics..
  • Uniprot
  • Purity
    Antigen affinity
  • Description
    Laminin subunit gamma-2 is a protein that in humans is encoded by the LAMC2 gene. Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. This gene encodes the gamma chain isoform laminin, gamma2. The gamma2 chain, formerly though to be a truncated version of beta chain(B2t), is highly homologous to the gamma1 chain; however, it lacks domain VI, and domains V, IV and III are shorter. It is expressed in several fetal tissues but differently from gamma1, and is specifically localized to epithelial cells in skin, lung and kidney. The epithelium-specific expression of the gamma 2 chain implied its role as an epithelium attachment molecule, and mutations in this gene have been associated with junctional epidermolysis bullosa, a skin disease characterized.
  • Immunogen
    An amino acid sequence from the C-terminus of LAMC2 (ETSIDGILADVKNLENIRDNL) was used as the immunogen for this LAMC2 antibody (100% homologous in human, mouse and rat).
  • Storage
    After reconstitution, the LAMC2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
  • Properties
    If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
  • Gene target
  • Gene symbol
    LAMC1-AS1, LAMC2
  • Short name
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Rabbit IgG
  • Alternative name
    Antibodies to LAMC2
  • Alternative technique
  • Alternative to gene target
    laminin, gamma 2, B2T and BM600 and CSF and EBR2 and EBR2A and LAMB2T and LAMNB2, LAMC2 and IDBG-105293 and ENSG00000058085 and 3918, heparin binding, Extracellular, Lamc2 and IDBG-198823 and ENSMUSG00000026479 and 16782, LAMC2 and IDBG-637198 and ENSBTAG00000000793 and 511043
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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