Kallikrein 8 Antibody / KLK8

• Catalog number
  R32442
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  Kallikrein 8 / KLK8
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 0.5-1ug/ml
• Added buffer
  Lyophilized from 1X Phosphate Buffered Saline (PBS) with 2.5% BSA and 0.025% sodium azide
• Intented use
  This KLK8 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  O60259
• Purity
  Antigen affinity
• Description
  Kallikrein-8 is a protein that in humans is encoded by the KLK8 gene. Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in tandem in a gene cluster on chromosome 19. The encoded protein may be involved in proteolytic cascade in the skin and may serve as a biomarker for ovarian cancer. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.
• Immunogen
  Amino acids V33-G260 were used as the immunogen for the KLK8 antibody.
• Storage
  Prior to reconstitution, store at 4oC. After reconstitution, the KLK8 antibody may be kept for up to one month refrigerated at +4 degrees C.For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Kallikrein   KLK8  
• Gene symbol
  KLK8
• Short name
  Anti- Kallikrein 8 / KLK8
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to Kallikrein 8 / KLK8
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6369
• Gene
  KLK8
• Long gene name
  kallikrein related peptidase 8
• Synonyms gene
  • PRSS19
• Synonyms gene name
  • kallikrein 8 (neuropsin/ovasin)
• Synonyms
  • HNP
  • TADG14
  • neuropsin
  • ovasin
• GenBank acession
  • AB008390
• Locus
  19q13.41
• Discovery year
  1999-09-09
• Entrez gene record
  11202
• Pubmed identfication
  • 10102990
  • 9714609
  • 16800724
  • 16800723
• RefSeq identity
  • NM_007196
• Classification
  • Kallikreins
  • Serine proteases
• VEGA ID
  OTTHUMG00000183086

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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