Cullin 1 Antibody / CUL1

• Catalog number
  R32221
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  Cullin 1 / CUL1
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 0.1-0.5ug/ml
• Notes
  Optimal dilution of the Cullin 1 antibody should be determined by the researcher.
• Intented use
  This Cullin 1 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q13616
• Purity
  Antigen affinity
• Description
  Cullin 1, also known as CUL1, is a human protein and gene from cullin family. This protein plays an important role in protein degradation and protein ubiquitination. This is an essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. Human cullin 1, but not the other closely related cullins 2, 3, 4A, and 5, selectively interacts with human SKP1.
• Immunogen
  Amino acids 457-770 of human Cullin 1 were used as the immunogen for the Cullin 1 antibody.
• Storage
  After reconstitution, the Cullin 1 antibody may be kept for up to one month refrigerated at +4 degrees C.For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Localization
  Nuclear, cytoplasmic
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Cullin   CUL1  
• Gene symbol
  CUL1
• Short name
  Anti-Cullin 1 / CUL1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to Cullin 1 / CUL1
• Alternative technique
  antibodies
• Alternative to gene target
  cullin 1, CUL1 and IDBG-46918 and ENSG00000055130 and 8454, ubiquitin protein ligase binding, nuclei, Cul1 and IDBG-143474 and ENSMUSG00000029686 and 26965, BT.36789 and IDBG-647000 and ENSBTAG00000047294 and

Gene info

• Identity
  HGNC:2551
• Gene
  CUL1
• Long gene name
  cullin 1
• GenBank acession
  • U58087
• Locus
  7q36.1
• Discovery year
  1998-10-29
• Entrez gene record
  8454
• Pubmed identfication
  • 8681378
• RefSeq identity
  • NM_003592
• Classification
  • Cullins
  • SCF complex
• VEGA ID
  OTTHUMG00000152776
• Locus Specific Databases
  • LRG_1407

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products