CCR6 Antibody

• Catalog number
  R30301
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  CCR6
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 0.5-1ug/ml
• Notes
  The stated application concentrations are suggested starting amounts. Titration of the CCR6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This CCR6 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P51684
• Purity
  Antigen affinity
• Description
  CCR6, also termed CKRL3, encodes a 369-amino acid polypeptide with greatest similarity to the family of alpha-chemokine-binding receptors. Unlike most chemokine receptor genes, it is encoded by more than 1 exon. Weakly expressed as a 4-kb transcript in spleen, lymph nodes, peripheral blood lymphocytes and appendix, CCR6 gene is located at 6q27. As the receptor for MIP-3-alpha, its activation leads to phospholipase C-dependent intracellular Ca(2+) mobilization. Additionally, CCR6 are markedly upregulated in psoriasis.
• Immunogen
  An amino acid sequence from the C-terminus of human CCR6 (RQTSETADNDNASSFTM) was used as the immunogen for this CCR6 antibody.
• Storage
  After reconstitution, the CCR6 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CCR6  
• Gene symbol
  CCR6
• Short name
  Anti-CCR6
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to CCR6
• Alternative technique
  antibodies
• Alternative to gene target
  chemokine (C-C motif) receptor 6, CCR6 and IDBG-99015 and ENSG00000112486 and 1235, C-C chemokine receptor activity, Plasma membranes, Ccr6 and IDBG-135484 and ENSMUSG00000040899 and 12458, BT.106551 and IDBG-647064 and ENSBTAG00000014496 and 519716

Gene info

• Identity
  HGNC:1607
• Gene
  CCR6
• Long gene name
  C-C motif chemokine receptor 6
• Synonyms gene
  • STRL22
• Synonyms gene name
  • chemokine (C-C motif) receptor 6
• Synonyms
  • CKR-L3
  • GPR-CY4
  • CMKBR6
  • GPR29
  • DRY-6
  • DCR2
  • BN-1
  • CD196
• GenBank acession
  • U68030
• Locus
  6q27
• Discovery year
  1997-04-21
• Entrez gene record
  1235
• Pubmed identfication
  • 8886020
• Classification
  • C-C motif chemokine receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000016015

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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