Als2Cr2 Antibody

• Catalog number
  N1046-100UG
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
• Form
  Purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  Als2Cr2
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 5-10ug/ml
• Notes
  Provided assay concentrations are suggestions only, Als2Cr2 antibody titration may be required for optimal results. This antibody will detect the 418 (ILPIP alpha) and 280 (ILPIP beta) amino acid isoforms.
• Added buffer
  1X Phosphate Buffered Saline (PBS), pH 7.4
• Intented use
  This Als2Cr2 antibodyis to be used only for research purposes and not for diagnostics..
• Gene ID
  55437
• Purity
  Purified by protein A Affinity Chromatography
• Description
  Als2Cr2, also called STE20-related kinase adapter protein beta (STRAD beta) and ILPIP, is a serine/threonine protein kinase encoded by the STRADB gene, discovered as an XIAP interacting protein. It is a mediator of the XIAP/TAK1 activation of the JNK1 pathway, an apoptosis inhibition mechanism independent of XIAP inhibition of caspases. Alone, it only moderately activates JNKs, but its interaction with XIAP/TAK1 induces a much stronger activation of JNK1, protecting against Caspase 1- or Fas-induced apoptosis.
• Immunogen
  A recombinant protein fragment from the interior region of human Als2Cr2 was used as the immunogen for this antibody.
• Storage
  Aliquot the Als2Cr2 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Als2Cr2  
• Gene symbol
  STRADB
• Short name
  Anti-Als2Cr2
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to Als2Cr2
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:13205
• Gene
  STRADB
• Long gene name
  STE20 related adaptor beta
• Synonyms gene
  • ALS2CR2
• Synonyms gene name
  • amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 2
  • STE20-related kinase adaptor beta
• Synonyms
  • CALS-21
  • PAPK
  • ILPIPA
  • ILPIP
• GenBank acession
  • AB038950
• Locus
  2q33.1
• Discovery year
  2001-02-13
• Entrez gene record
  55437
• Pubmed identfication
  • 11161814
  • 14511394
• RefSeq identity
  • NM_018571
• VEGA ID
  OTTHUMG00000132831

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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