ABCD2 Antibody

• Catalog number
  F42334-0.08ML
• Price
  Please ask
• Size
  0.08 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  ABCD2
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC, FACS, ELISA
• Recommended dilutions
  Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50
• Intented use
  This ABCD2 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q9UBJ2
• Purity
  Antigen affinity
• Description
  The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown; however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters. Mutations in this gene have been observed in patients with adrenoleukodystrophy, a severe demyelinating disease. This gene has been identified as a candidate for a modifier gene, accounting for the extreme variation among adrenoleukodystrophy phenotypes. This gene is also a candidate for a complement group of Zellweger syndrome, a genetically heterogeneous disorder of peroxisomal biogenesis.
• Immunogen
  A portion of amino acids 553-582 from the human protein was used as the immunogen for this ABCD2 antibody.
• Storage
  Aliquot the ABCD2 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Localization
  Cytoplasmic
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  ABCD2  
• Gene symbol
  ABCD2
• Short name
  Anti- ABCD2
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to ABCD2
• Alternative technique
  antibodies
• Alternative to gene target
  ATP-binding cassette, sub-family D (ALD), member 2, ABC39 and ALDL1 and ALDR and ALDRP and hALDR, ABCD2 and IDBG-26995 and ENSG00000173208 and 225, ATPase activity, Plasma membranes, Abcd2 and IDBG-175455 and ENSMUSG00000055782 and 26874, BT.87418 and IDBG-633512 and ENSBTAG00000038043 and 100335783,101909154,526436

Gene info

• Identity
  HGNC:66
• Gene
  ABCD2
• Long gene name
  ATP binding cassette subfamily D member 2
• Synonyms gene
  • ALDL1
• Synonyms gene name
  • ATP-binding cassette, sub-family D (ALD), member 2
• Synonyms
  • ALDR
  • ALDRP
• GenBank acession
  • U28150
• Locus
  12q12
• Discovery year
  1997-10-10
• Entrez gene record
  225
• Pubmed identfication
  • 8577752
• RefSeq identity
  • NM_005164
• Classification
  • ATP binding cassette subfamily D
• VEGA ID
  OTTHUMG00000169337

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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