Z-D (OMe)E (OMe)VD (OMe)-FMK [Caspase-3/Caspase-7 Inhibitor (FMK)]

Products_type

Peptide
Products_short_name

[Z-D (OMe)E (OMe)VD (OMe)-FMK]
Purity

>=95% (TLC)
Form

Lyophilized
Storage_stability

For long term storage, store at -20 degree CStable for 1 year after receipt when stored at -20 degree C
Description

Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways. Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.

Gene target

Z-D OMe OMe OMe FMK [Caspase-3/Caspase-7 Inhibitor FMK
Gene symbol

PSMB7, PLA2G4F, SNAR-D, HLA-Z, DGCR11, LY6G6D, OR1L3, ULK4P2
Short name

Z-D (OMe)E (OMe)VD (OMe)-FMK [Caspase-3/Caspase-7 Inhibitor (FMK)]
Alternative name

Z-D (OMe)E (OMe)VD (OMe)-FMK [caspase-3/caspase-7 suppressor (FMK)]

Identity

HGNC:9544
Gene

PSMB7
Long gene name

proteasome 20S subunit beta 7
Synonyms gene name
- proteasome (prosome, macropain) subunit, beta type, 7
- proteasome subunit beta 7
Synonyms
- Z
Synonyms name
- proteasome subunit β2
GenBank acession
- AJ420455
Locus

9q33.3
Discovery year

1995-11-22
Entrez gene record

5695
Pubmed identfication
- 8811196
RefSeq identity
- NM_002799
Classification
- Proteasome
VEGA ID

OTTHUMG00000021042

Identity

HGNC:17226
Gene

DGCR11
Long gene name

DiGeorge syndrome critical region gene 11
Synonyms gene name
- DiGeorge syndrome critical region gene 11
- DiGeorge syndrome critical region gene 11 (non-protein coding)
Synonyms
- DGS-D
GenBank acession
- L77561
Locus

22q11.21
Discovery year

2002-11-13
Entrez gene record

25786
Pubmed identfication
- 8776594
Classification
- Long non-coding RNAs with non-systematic symbols
VEGA ID

OTTHUMG00000186100

Identity

HGNC:13935
Gene

LY6G6D
Long gene name

lymphocyte antigen 6 family member G6D
Synonyms gene
- C6orf23
Synonyms gene name
- chromosome 6 open reading frame 23
- lymphocyte antigen 6 complex, locus G6D
Synonyms
- MEGT1
- Ly6-D
- G6D
- LY6-D
- NG25
Locus

6p21.33
Discovery year

2002-04-05
Entrez gene record

58530
Pubmed identfication
- 12079290
Classification
- LY6/PLAUR domain containing
VEGA ID

OTTHUMG00000137370

Identity

HGNC:15776
Gene

ULK4P2
Long gene name

ULK4 pseudogene 2
Synonyms gene
- FAM7A2
Synonyms gene name
- family with sequence similarity 7, member A2
- unc-51-like kinase 4 (C. elegans) pseudogene 2
Synonyms
- D-X
Locus

15q13.2
Discovery year

2001-06-29
Entrez gene record

100288380
Pubmed identfication
- 11829490
VEGA ID

OTTHUMG00000175653

Name

Models, Chemical
Concept

Scope note: Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
Tree numbers
- E05.599.495