TrkB (Tyrosine Kinase Receptor B) (BDNF/NT-3 growth factors receptor, Neurotrophic tyrosine kinase receptor type 2, TrkB tyrosine kinase, GP145-TrkB/GP95-TrkB, Trk-B) (Ntrk2)

• Catalog number
  MBS621407
• Price
  Please ask
• Size
  0.1 mL

• Products_type
  Antibody
• Products_short_name
  [TrkB]
• Products_name_syn
  [Anti -TrkB (Tyrosine Kinase Receptor B) (BDNF/NT-3 growth factors receptor, Neurotrophic tyrosine kinase receptor type 2, TrkB tyrosine kinase, GP145-TrkB/GP95-TrkB, Trk-B) (Ntrk2)]
• Other_names
  [trkB; BDNF/NT-3 growth factors receptor; BDNF/NT-3 growth factors receptor; trk-B; OTTHUMP00000021573; OTTHUMP00000021574; OTTHUMP00000021575; OTTHUMP00000021576; OTTHUMP00000021577; trkB tyrosine kinase; tyrosine kinase receptor B; BDNF-tropomyosine receptor kinase B; neurotrophic tyrosine kinase, receptor, type 2; GP145-TrkB; Trk-B; Neurotrophic tyrosine kinase receptor type 2; TrkB tyrosine kinase]
• Other_gene_names
  [NTRK2; NTRK2; TRKB; GP145-TrkB; TRKB]
• Clonality
  Polyclonal
• Reactivity
  Mouse, Rat
• Specificity
  Recognizes rat and mouse TrkB.
• Purity
  Serum Serum
• Form
  Supplied as a lyophilized powder. Reconstitute with 100ul sterile ddH2O.
• Storage_stability
  Lyophilized powder may be stored at -20 degree C. Reconstitute with sterile buffer or ddH2O. Aliquot and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
• Tested_application
  ELISA (EL/EIA), Immunohistochemistry (IHC)
• Description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  TrkB   Tyrosine   Kinase   Receptor   BDNF/NT-3   growth   factors   receptor   Neurotrophic   tyrosine   kinase   receptor   TrkB   tyrosine   kinase   GP145-TrkB/GP95-TrkB   Trk-B   Ntrk2  
• Gene symbol
  SORT1, BDNF, BDNF-AS, NTF4, MIR1302-3, MIR509-3, MIR7-3, PIRC14
• Short name
  TrkB (Tyrosine Kinase Receptor B) (BDNF/NT-3 growth factors receptor, Neurotrophic tyrosine kinase receptor 2, TrkB tyrosine kinase, GP145-TrkB/GP95-TrkB, Trk-B) (Ntrk2)
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  TrkB (Tyrosine phosphorylation catalyst Receptor B) (brain-derived neurotrophic factor/NT-3 growth factors receptor, Neurotrophic tyrosine phosphorylation catalyst receptor classification 2, TrkB tyrosine phosphorylation catalyst, GP145-TrkB/GP95-TrkB, Trk-B) (Ntrk2)
• Alternative to gene target
  brain-derived neurotrophic factor, ANON2 and BULN2, BDNF and IDBG-36817 and ENSG00000176697 and 627, growth factor activity, Extracellular, Bdnf and IDBG-195506 and ENSMUSG00000048482 and 12064, BDNF and IDBG-636102 and ENSBTAG00000008134 and 617701

Gene info

• Identity
  HGNC:11186
• Gene
  SORT1
• Long gene name
  sortilin 1
• Synonyms
  • Gp95
  • NT3
• GenBank acession
  • BC023542
• Locus
  1p13.3
• Discovery year
  1996-05-14
• Entrez gene record
  6272
• RefSeq identity
  • NM_002959
• VEGA ID
  OTTHUMG00000011999

Gene info

• Identity
  HGNC:1033
• Gene
  BDNF
• Long gene name
  brain derived neurotrophic factor
• Synonyms name
  • neurotrophin
• GenBank acession
  • AB038670
• Locus
  11p14.1
• Discovery year
  1991-01-15
• Entrez gene record
  627
• Pubmed identfication
  • 2236018
  • 1889806
  • 17942328
  • 17493809
• RefSeq identity
  • NM_170735
• Classification
  • Neurotrophins
• VEGA ID
  OTTHUMG00000178797

Gene info

• Identity
  HGNC:20608
• Gene
  BDNF-AS
• Long gene name
  BDNF antisense RNA
• Synonyms gene
  • BDNFOS
• Synonyms gene name
  • BDNF opposite strand (non-protein coding)
  • BDNF antisense RNA (non-protein coding)
• Synonyms
  • BT2A
  • BT2B
  • BT2C
  • BT2D
  • NCRNA00049
  • BDNF-AS1
  • BDNFAS
• Synonyms name
  • non-protein coding RNA 49
  • BDNF antisense RNA 1 (non-protein coding)
• GenBank acession
  • AY054391
• Locus
  11p14.1
• Discovery year
  2005-02-01
• Entrez gene record
  497258
• Pubmed identfication
  • 15666411
  • 22446693
  • 28777258
• RefSeq identity
  • NR_002832
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:8024
• Gene
  NTF4
• Long gene name
  neurotrophin 4
• Synonyms gene
  • NTF5
• Synonyms gene name
  • neurotrophin 5 (neurotrophin 4/5)
• Synonyms
  • NT-4/5
  • GLC1O
• Synonyms name
  • neurotrophic factor 4
• Locus
  19q13.33
• Discovery year
  1992-10-15
• Entrez gene record
  4909
• Pubmed identfication
  • 1496419
• RefSeq identity
  • NM_006179
• Classification
  • Neurotrophins
• VEGA ID
  OTTHUMG00000191728

Gene info

• Identity
  HGNC:35295
• Gene
  MIR1302-3
• Long gene name
  microRNA 1302-3
• Synonyms gene
  • MIRN1302-3
• Synonyms
  • hsa-mir-1302-3
• Locus
  2q14.1
• Discovery year
  2008-11-03
• Entrez gene record
  100302128
• RefSeq identity
  • NR_031632
• Classification
  • MicroRNA MIR1302 family

Gene info

• Identity
  HGNC:33675
• Gene
  MIR509-3
• Long gene name
  microRNA 509-3
• Synonyms gene
  • MIRN509-3
• Synonyms
  • hsa-mir-509-3
• Locus
  Xq27.3
• Discovery year
  2007-10-24
• Entrez gene record
  100126337
• RefSeq identity
  • NR_030629
• Classification
  • MicroRNA MIR506 family

Gene info

• Identity
  HGNC:31640
• Gene
  MIR7-3
• Long gene name
  microRNA 7-3
• Synonyms gene
  • MIRN7-3
• Synonyms
  • hsa-mir-7-3
• Locus
  19p13.3
• Discovery year
  2004-04-23
• Entrez gene record
  407045
• RefSeq identity
  • NR_029607
• Classification
  • MicroRNA MIR7 family

Gene info

• Identity
  HGNC:37518
• Gene
  PIRC14
• Long gene name
  piwi-interacting RNA cluster 14
• Locus
  3
• Discovery year
  2009-11-05
• Entrez gene record
  100313784
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

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