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Products_type
Antibody
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Products_short_name
[TrkA]
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Products_name_syn
[Anti -TrkA, phosphorylated (Tyr490) (Tyrosine Kinase Receptor A, Nerve Growth Factor Receptor, NGFR, Neurotrophin Receptor, NTR)]
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Other_names
[TRKA; High affinity nerve growth factor receptor; high affinity nerve growth factor receptor; Oncogene TRK; OTTHUMP00000038736; OTTHUMP00000234666; OTTHUMP00000234667; OTTHUMP00000234668; OTTHUMP00000234669; tyrosine kinase receptor A; TRK1-transforming tyrosine kinase protein; neurotrophic tyrosine kinase, receptor, type 1; Neurotrophic tyrosine kinase receptor type 1; TRK1-transforming tyrosine kinase protein; p140-TrkA]
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Other_gene_names
[NTRK1; NTRK1; MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA; DKFZp781I14186; TRK]
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Clonality
Polyclonal
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Reactivity
Human, Mouse, Rat
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Specificity
Recognizes endogenous levels of rat Trk only when phosphorylated at Tyr490. Can also detect the corresponding residues of phosphorylated TrkB and TrkC. Species sequence homology: human, mouse.
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Purity
Affinity Purified Purified by Protein A affinity chromatography.
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Form
Supplied as liquid in 10mM HEPES, pH 7.5, 150mM sodium chloride, 0.1mg/ml BSA, 50% glycerol. No preservative added.
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Storage_stability
May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested_application
ELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP)
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Description
Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbol
NGFR-AS1, NTSR1, NGFR
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Short name
TrkA, phosphorylated (Tyr490) (Tyrosine Kinase Receptor A, Nerve Growth Factor Receptor, NGFR, Neurotrophin Receptor, NTR)
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Host
Rabbit
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Isotype
IgG
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Alternative name
TrkA, phosphorylated (Tyr490) (Tyrosine phosphorylation catalyst Receptor A, Nerve Growth Factor Receptor, nerve growth factor receptor, Neurotrophin Receptor, NTR)
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Alternative to gene target
nerve growth factor receptor, CD271 and Gp80-LNGFR and p75(NTR) and p75NTR and TNFRSF16, NGFR and IDBG-57653 and ENSG00000064300 and 4804, nerve growth factor binding, nuclei, Ngfr and IDBG-209608 and ENSMUSG00000000120 and 18053, NGFR and IDBG-638806 and ENSBTAG00000020979 and 353110
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Tissue
nerve
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