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Products_type
Antibody
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Products_short_name
[STAT 5]
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Products_name_syn
[Anti -STAT 5, phosphorylated (Tyr694) (Signal Transducer and Activator of Transcription 5, STAT5, Signal Transducer and Activator of Transcription 5A, STAT5A, STAT5B, Signal Transducer And Activator Of Transcription 5B)]
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Other_names
[Signal-transducer and activator of transcription protein at 92E, isoform M; Signal transducer and transcription activator; CG4257 gene product from transcript CG4257-RH; CG4257-PB; CG4257-PC; CG4257-PE; CG4257-PF; CG4257-PG; CG4257-PH; CG4257-PI; CG4257-PJ; CG4257-PK; CG4257-PL; CG4257-PM; Signal-transducer and activator of transcription protein; Signal-transducer and activator of transcription protein at 92E; Stat92E-PB; Stat92E-PC; Stat92E-PE; Stat92E-PF; Stat92E-PG; Stat92E-PH; Stat92E-PI; Stat92E-PJ; Stat92E-PK; Stat92E-PL; Stat92E-PM; marelle; signal transducer and activator of transcription; signal transducers and activator of transcription; Signal-transducer and activator of transcription protein at 92E; Protein marelle]
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Other_gene_names
[Stat92E; Stat92E; CG4257; d-STAT; D-stat; D-Stat; D-STAT; D-stat/stat92E; DmelCG4257; DmSTAT; DRODSRC; DSRC; dstat; dSTAT; Dstat; DSTAT; Dstat 92E; dSTAT92E; Dstat92E; dSTAT92E/marelle; l(3)06346; l(3)j6C8; mrl; mrL; mrl stat92E; pSTAT; SD-stat; stat; Stat; STAT; STAT 92E;; MARE; mrL; Stat; d-STAT]
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Clonality
Polyclonal
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Reactivity
Human, Mouse, Rat
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Specificity
Recognizes endogenous levels of human STAT5 when phosphorylated at tyrosine 694. Species Crossreactivity: mouse and rat
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Purity
Affinity Purified Purified by immunoaffinity chromatography.
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Form
Supplied as a liquid in PBS (without Mg2+ and Ca2+), pH 7.4, 0.02% sodium azide, 50% glycerol.
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Storage_stability
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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Tested_application
Western Blot (WB), Immunohistochemistry (IHC)
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Description
STAT proteins are phosphorylated by receptor related kinases and for homo or hetero dimers. JAK-STAT pathways are signaling to the nucleus of the cell. The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
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Gene target
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Gene symbol
STAT5A, STAT5B, STAT6, SOAT1
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Short name
STAT 5, phosphorylated (Tyr694) (Signal Transducer Activator of Transcription 5, STAT5, Signal Transducer Activator of Transcription 5A, STAT5A, STAT5B, Signal Transducer Activator Of Transcription 5B)
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Host
Rabbit
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Isotype
IgG
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Alternative name
Signal transducer and activation on transcription 5, phosphorylated (Tyr694) (Signal Transducer and Activator on Transcription 5, STAT5, Signal Transducer and Activator on Transcription 5A, signal transducer and activator on transcription 5A, signal transducer and activator on transcription 5B, Signal Transducer And Activator on Transcription 5B)
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Alternative to gene target
signal transducer and activator of transcription 5B, STAT5, STAT5B and IDBG-50532 and ENSG00000173757 and 102723386,6777, protein dimerization activity, nuclei, Stat5b and IDBG-211594 and ENSMUSG00000020919 and 20851, STAT5B and IDBG-640180 and ENSBTAG00000010125 and 282376,789476
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