Serotonin Receptor 1A (5-HT1A)

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Description

The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

Gene target

Serotonin Receptor 5-HT1A
Gene symbol

HTR1A, MIR1302-5, PIRC22, PIRC23, PIRC20, PIRC21, HTR6, IGKV3OR2-5, IGHV2OR16-5, SNORD116-5
Short name

Serotonin Receptor 1A (5-HT1A)
Alternative name

Serotonin Receptor 1A (5-HT1A)

Identity

HGNC:5286
Gene

HTR1A
Long gene name

5-hydroxytryptamine receptor 1A
Synonyms gene
- ADRB2RL1
- ADRBRL1
Synonyms gene name
- 5-hydroxytryptamine (serotonin) receptor 1A
- 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
Synonyms
- 5-HT1A
GenBank acession
- AF498978
Locus

5q12.3
Discovery year

1986-01-01
Entrez gene record

3350
Pubmed identfication
- 2591972
- 12969265
RefSeq identity
- NM_000524
Classification
- 5-hydroxytryptamine receptors, G protein-coupled
VEGA ID

OTTHUMG00000162279

Identity

HGNC:5301
Gene

HTR6
Long gene name

5-hydroxytryptamine receptor 6
Synonyms gene name
- 5-hydroxytryptamine (serotonin) receptor 6
- 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
Synonyms
- 5-HT6
- 5-HT6R
GenBank acession
- L41147
Locus

1p36.13
Discovery year

1997-12-11
Entrez gene record

3362
Pubmed identfication
- 8522988
RefSeq identity
- NM_000871
Classification
- 5-hydroxytryptamine receptors, G protein-coupled
VEGA ID

OTTHUMG00000002713

Identity

HGNC:5832
Gene

IGKV3OR2-5
Long gene name

immunoglobulin kappa variable 3/OR2-5 (pseudogene)
Synonyms gene name
- immunoglobulin kappa variable 3/OR2-5
- immunoglobulin kappa variable 3/OR2-5 pseudogene
Synonyms
- IGKV3/OR2-5
GenBank acession
- X51882
Locus

2q11.2
Discovery year

2000-04-18
Entrez gene record

28854
Classification
- Immunoglobulin kappa (IGK) orphons
VEGA ID

OTTHUMG00000184519