Ryanodine Receptor (RyR, RYDR, ARVC2, ARVD2, Brain Ryanodine Receptor Calcium Release Channel, Brain-type Ryanodine Receptor, Cardiac Muscle Ryanodine Receptor, Cardiac Muscle Ryanodine Receptor Calcium Release Channel, Cardiac Muscle Type Ryanodine Recep

• Catalog number
  MBS602690
• Price
  Please ask
• Size
  0.1 mL

• Products_type
  Antibody
• Products_short_name
  [Ryanodine Receptor]
• Products_name_syn
  [Anti -Ryanodine Receptor (RyR, RYDR, ARVC2, ARVD2, Brain Ryanodine Receptor Calcium Release Channel, Brain-type Ryanodine Receptor, Cardiac Muscle Ryanodine Receptor, Cardiac Muscle Ryanodine Receptor Calcium Release Channel, Cardiac Muscle Type Ryanodine Recep]
• Other_names
  [ryanodine receptor; Type 1-like ryanodine receptor; ryanodine receptor 1; ryanodine receptor type1; central core disease of muscle; type 1-like ryanodine receptor; skeletal muscle ryanodine receptor; skeletal muscle calcium release channel; sarcoplasmic reticulum calcium release channel; ryanodine receptor 1 (skeletal)]
• Other_gene_names
  [RYR1; CCO; MHS; RYR; MHS1; RYDR; SKRR; RYR-1]
• Clonality
  Monoclonal
• Clone
  [9C106]
• Reactivity
  Canine, Chicken, Guinea Pig, Rabbit, Rat
• Specificity
  Detects ryanodine receptor 2 (RyR 2) and weakly detects RyR 1. Species Crossreactivity: Crossreacts with Rabbit, Rat, Canine, Guinea pig, Chicken, Fish and Amphibians. Not yet tested in other species.
• Purity
  Ascites
• Form
  Supplied as a liquid in PBS, pH 7.2, 0.05% sodium azide.
• Storage_stability
  May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degree C. Aliquots are stable for at least 3 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
• Tested_application
  Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
• Description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  Ryanodine   Receptor   RyR   RYDR   ARVC2   ARVD2   Brain   Ryanodine   Receptor   Calcium   Release   Channel   Brain   Ryanodine   Receptor   Cardiac   Muscle   Ryanodine   Receptor   Cardiac   Muscle   Ryanodine   Receptor   Calcium   Release   Channel   Cardiac   Muscle   Ryanodine   Recep  
• Gene symbol
  RYR2
• Short name
  Ryanodine Receptor (RyR, RYDR, ARVC2, ARVD2, Brain Ryanodine Receptor Calcium Release Channel, Brain- Ryanodine Receptor, Cardiac Muscle Ryanodine Receptor, Cardiac Muscle Ryanodine Receptor Calcium Release Channel, Cardiac Muscle Ryanodine Recep
• Host
  Mouse
• Isotype
  IgG1
• Alternative name
  Ryanodine Receptor (RyR, RYDR, ARVC2, ARVD2, Brain Ryanodine Receptor Calcium Release Channel, Brain-classification Ryanodine Receptor, Cardiac Muscle Ryanodine Receptor, Cardiac Muscle Ryanodine Receptor Calcium Release Channel, Cardiac Muscle classification Ryanodine Recep
• Tissue
  brain, muscle

Gene info

• Identity
  HGNC:10484
• Gene
  RYR2
• Long gene name
  ryanodine receptor 2
• Synonyms gene
  • ARVD2
• Synonyms gene name
  • arrhythmogenic right ventricular dysplasia 2
  • ryanodine receptor 2 (cardiac)
• Synonyms
  • ARVC2
  • VTSIP
• GenBank acession
  • X91869
• Locus
  1q43
• Discovery year
  1989-12-07
• Entrez gene record
  6262
• Pubmed identfication
  • 2380170
  • 8406504
  • 11159936
• RefSeq identity
  • NM_001035
• Classification
  • Ryanodine receptors
  • Armadillo like helical domain containing
  • EF-hand domain containing
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000039543
• Locus Specific Databases
  • Gene Connection for the Heart - Catecholaminergic Polymorphic Ventricular Tachy cardia database
  • LRG_402

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