Recombinant Pygathrix nemaeus C-C chemokine receptor type 5 (CCR5)

Products_type

Recombinant Protein
Products_short_name

[C-C chemokine receptor type 5 (CCR5)]
Products_name_syn

[Recombinant C-C chemokine receptor type 5 (CCR5); C-C chemokine receptor type 5; C-C CKR-5; CC-CKR-5; CCR-5; CCR5; CD_antigen= CD195]
Other_names

[C-C chemokine receptor type 5; C-C chemokine receptor type 5]
Products_gene_name_syn

[CCR5; CMKBR5]
Other_gene_names

[CCR5; CMKBR5; C-C CKR-5; CC-CKR-5; CCR-5; CCR5]
Purity

>=90%
Form

Lyophilized or liquid (Format to be determined during the manufacturing process)
Storage_stability

Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
Description

Chemokines, chemokine receptors, ligands , motif chemokines and cytokines are supplied by MyBioSource in 1. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
Source

Recombinants or rec. proteins
Group

recombinants

Gene target

Pygathrix nemaeus C-C chemokine receptor CCR5
Gene symbol

SMC4, PCK1, MYB, SFTPC, VCX3B, MAF, RFX1, EGR4, P4HA2
Short name

Recombinant Pygathrix nemaeus C-C chemokine receptor 5 (CCR5)
Technique

Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
Host

E Coli or Yeast or Baculovirus or Mammalian Cell
Alternative name

Rec. Pygathrix nemaeus C-C chemokine receptor classification 5 (chemokine (C-C motif) receptor 5 (gene/pseudogene))
Alternative technique

rec
Alternative to gene target

chemokine (C-C motif) receptor 5 (gene/pseudogene), CC-CKR-5 and CCCKR5 and CCR-5 and CD195 and CKR-5 and CKR5 and CMKBR5 and IDDM22, CCR5 and IDBG-30229 and ENSG00000160791 and 1234, chemokine (C-C motif) ligand 5 binding, Cell surfaces, CCR5 and IDBG-646247 and ENSBTAG00000008099 and 497017

Identity

HGNC:14013
Gene

SMC4
Long gene name

structural maintenance of chromosomes 4
Synonyms gene
- SMC4L1
Synonyms gene name
- SMC4 (structural maintenance of chromosomes 4, yeast)-like 1
- SMC4 structural maintenance of chromosomes 4-like 1 (yeast)
Synonyms
- hCAP-C
- CAP-C
GenBank acession
- AF092564
Locus

3q25.33
Discovery year

2001-02-22
Entrez gene record

10051
Pubmed identfication
- 9789013
- 10319587
Classification
- Structural maintenance of chromosomes proteins
- Condensin I subunits
- Condensin II subunits
- MicroRNA protein coding host genes
VEGA ID

OTTHUMG00000159006

Identity

HGNC:6776
Gene

MAF
Long gene name

MAF bZIP transcription factor
Synonyms gene name
- v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
Synonyms
- c-MAF
Locus

16q23.2
Discovery year

1991-08-01
Entrez gene record

4094
Pubmed identfication
- 14998484
Classification
- Basic leucine zipper proteins
VEGA ID

OTTHUMG00000137621

Identity

HGNC:9982
Gene

RFX1
Long gene name

regulatory factor X1
Synonyms gene name
- regulatory factor X, 1 (influences HLA class II expression)
Synonyms
- EF-C
Synonyms name
Locus

19p13.12
Discovery year

1991-11-06
Entrez gene record

5989
Pubmed identfication
- 1505960
- 8289803
RefSeq identity
- NM_002918
Classification
- Regulatory factor X family
VEGA ID

OTTHUMG00000181979

Identity

HGNC:8547
Gene

P4HA2
Long gene name

prolyl 4-hydroxylase subunit alpha 2
Synonyms gene name
- procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide II
- prolyl 4-hydroxylase, alpha polypeptide II
Synonyms
- C-P4Halpha(II)
Synonyms name
- 4-PH alpha 2
- collagen prolyl 4-hydroxylase alpha(II)
GenBank acession
- U90441
Locus

5q31.1
Discovery year

1999-02-23
Entrez gene record

8974
Pubmed identfication
- 9211872
- 9149945
RefSeq identity
- NM_004199
Classification
- MicroRNA protein coding host genes
VEGA ID

OTTHUMG00000059647

Name

Primary Cell Culture
Concept

Scope note: The initial culturing of cells derived directly from fresh TISSUES.
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data