Rabbit Polyclonal (IgG) to Human LIG1 / DNA Ligase 1[LIG1 / DNA Ligase 1]
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Catalog number
MBS247419
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Price
Please ask
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Size
NA
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Products_type
Antibody
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Products_gene_name
[LIG1]
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Reactivity
Human
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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About
Immunoglobulin gamma, IgG, mouse monoclonal H&L chain clones or rabbit, goat polyclonal antibodies have 4 parts. There are 2 heavy chains, 2 light chains. The IgG antibody has 2 antigen binding sites. They represent 70% or more of serum antibodies. This antibody can be antigen purified or protein A or G purified. For storage sodium azide is added or you can call us to request azide free antibody preparations. These will need colder storage temperatures. Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera. Rabbits are used for polyclonal antibody production by MyBioSource. Rabbit antibodies are very stable and can be stored for several days at room temperature. MyBioSource adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Group
Polyclonals and antibodies
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Latin name
Oryctolagus cuniculus
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Gene target
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Gene symbol
LIG1, LRIG1, PRKDC, HLA-DOA
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Short name
Rabbit Polyclonal (IgG) LIG1 / DNA Ligase 1[LIG1 / DNA Ligase 1]
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Technique
Polyclonal, Rabbit, dna, IgG, IgGs, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
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Host
Rabbit, Rabbits
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Isotype
IgG, IgG
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Species
Human, Humans
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Alternative name
production species: rabbit polyclonal (Immunoglobulin G) to H. sapiens LIG1 / Desoxyribonucleic acid Ligase 1[LIG1 / Desoxyribonucleic acid Ligase 1]
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Alternative technique
polyclonals, rabbit-anti, immunoglobulins
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Gene info
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Identity
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Gene
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Long gene name
DNA ligase 1
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Synonyms gene name
- ligase I, DNA, ATP-dependent
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Synonyms name
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Locus
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Discovery year
1991-05-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Nucleotide excision repair
- DNA ligases
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VEGA ID
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Locus Specific Databases
Gene info
Gene info
Gene info
MeSH Data
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Name
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Concept
Scope note:
A DNA amplification technique based upon the ligation of OLIGONUCLEOTIDE PROBES. The probes are designed to exactly match two adjacent sequences of a specific target DNA. The chain reaction is repeated in three steps in the presence of excess probe: (1) heat denaturation of double-stranded DNA, (2) annealing of probes to target DNA, and (3) joining of the probes by thermostable DNA ligase. After the reaction is repeated for 20-30 cycles the production of ligated probe is measured.
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Tree numbers
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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