RABBIT ANTI HUMAN CNTF

• Catalog number
  MBS221547
• Price
  Please ask
• Size
  0.1 mg

• Products_type
  Antibody
• Products_short_name
  [CNTF]
• Other_names
  [ciliary neurotrophic factor; Ciliary neurotrophic factor; ciliary neurotrophic factor; ciliary neurotrophic factor]
• Products_gene_name
  [CNTF]
• Other_gene_names
  [CNTF; CNTF; HCNTF; CNTF]
• Clonality
  Polyclonal
• Specificity
  This product recognises human CNTF (ciliary neurotrophic factor), a 200 amino acid homodimeric neurotrophic and differentiation factor of the CNTF family, which supports the survival and differentiation of several motor neuron types within the nervous system, but also affects other target tissues, including skeletal muscle (Vergara, C. & Ramirez, B.), glial cells, hepatocytes and embryonic stem cells.CNTF mainly signals through binding to a receptor complex consisting of a CNTFRa subunit, two beta components, gp130 and LIFR, resulting ultimately in the activation of JAK/STAT signalling pathway, but CNTF has also been shown to bind to the receptor for interleukin-6 (IL-6R).
• Form
  Purified Purified IgG - lyophilised
• Concentration
  IgG concentration 1.0mg/ml
• Storage_stability
  Prior to reconstitution store at 4 degree C. After reconstitution store at -20 degree C. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 12 months from date of reconstitution.
• Tested_application
  ELISA (EIA), Functional Assays (FN), Immunohistology Paraffin, Western Blot (WB)
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• About
  Rabbits are used for polyclonal antibody production by MyBioSource. Rabbit antibodies are very stable and can be stored for several days at room temperature. MyBioSource adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus

• Gene target
  CNTF  
• Gene symbol
  ZFP91-CNTF, CNTF
• Short name
  RABBIT ANTI CNTF
• Technique
  anti human, Rabbit, anti, antibody to, anti human antibodies
• Host
  Rabbit, Rabbits
• Isotype
  IgG
• Species
  Human, Humans
• Alternative name
  production species: rabbit antibody to H. sapiens ciliary neurotrophic factor
• Alternative technique
  rabbit-anti, antibodies
• Alternative to gene target
  ciliary neurotrophic factor, HCNTF, CNTF and IDBG-409278 and ENSG00000242689 and 1270, growth factor activity, Extracellular, Cntf and IDBG-254935 and ENSMUSG00000079415 and 12803, CNTF and IDBG-637978 and ENSBTAG00000003624 and 100848228

Gene info

• Identity
  HGNC:33441
• Gene
  ZFP91-CNTF
• Long gene name
  ZFP91-CNTF readthrough (NMD candidate)
• GenBank acession
  • AB057443
• Locus
  11q12.1
• Discovery year
  2011-05-31
• Entrez gene record
  386607
• Pubmed identfication
  • 12738986
• RefSeq identity
  • NR_024091
• VEGA ID
  OTTHUMG00000166280

Gene info

• Identity
  HGNC:2169
• Gene
  CNTF
• Long gene name
  ciliary neurotrophic factor
• Synonyms
  • HCNTF
• Synonyms name
  • Ciliary Neuronotrophic Factor
• GenBank acession
  • BC068030
• Locus
  11q12.1
• Discovery year
  1991-01-07
• Entrez gene record
  1270
• Pubmed identfication
  • 1840538
  • 1714745
• RefSeq identity
  • NM_000614
• Classification
  • Interleukin 6 type cytokine family
• VEGA ID
  OTTHUMG00000137476
• Locus Specific Databases
  • ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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