Nanog (Embryonic Stem Cell Specific Homeobox Protein, FLJ12581, FLJ40451, hNanog, Homeobox Protein NANOG, Homeobox Transcription Factor Nanog, Nanog Homeobox)[Nanog]

• Catalog number
  MBS623275
• Price
  Please ask
• Size
  NA

• Products_type
  Antibody
• Reactivity
  Human
• Description
  For cells, cell lines and tissues in culture till half confluency. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
• Test
  Stem cell factors and stem cell growth factors will produce stem cells or be part of a transdifferentiation process to produce other cells. A cell can transdifferentiate by going back to the naive stem cell stadium or directly into the other cell, helped by the stem cell and transdifferentiationf actors. Stem cell growth factors or stem cell factors are mostly used to produce iPSCs or induced pluripotent stem cells by Jamaka or Thomson factors by using for example 5 Lenti-III-CMV viruses, expressing the Yamanaka iPSC factor set (Oct4, Sox2, Nanog and Lin28) + GFP positive control. Trans differentiation will omit the stem cell stadium but stem cell factors sill play an important role in trans differentiation strategies.

• Gene target
  Nanog   Embryonic   Stem   Specific   Homeobox   Protein   FLJ12581   FLJ40451   hNanog   Homeobox   Protein   NANOG   Homeobox   Transcription   Factor   Nanog   Nanog   Homeobox   [Nanog]  
• Gene symbol
  NANOG
• Short name
  Nanog (Embryonic Stem Specific Homeobox Protein, FLJ12581, FLJ40451, hNanog, Homeobox Protein NANOG, Homeobox Transcription Factor Nanog, Nanog Homeobox)[Nanog]
• Host
  Rabbit
• Alternative name
  Nanog (Embryonic progenitor cellular Specific Homeobox Protein, FLJ12581, FLJ40451, hNanog, Homeobox Protein NANOG, Homeobox Transcription Factor Nanog, Nanog Homeobox)[Nanog]
• Tissue
  cell, stem

Gene info

• Identity
  HGNC:20857
• Gene
  NANOG
• Long gene name
  Nanog homeobox
• Synonyms
  • FLJ12581
  • FLJ40451
• GenBank acession
  • AB093576
• Locus
  12p13.31
• Discovery year
  2003-09-10
• Entrez gene record
  79923
• Pubmed identfication
  • 12787505
  • 12787504
• RefSeq identity
  • NM_024865
• Classification
  • NKL subclass homeoboxes and pseudogenes
• VEGA ID
  OTTHUMG00000166019

MeSH Data

• Name
  Embryo Research
• Concept
  Scope note: Experimentation on, or using the organs or tissues from, a human or other mammalian conceptus during the prenatal stage of development that is characterized by rapid morphological changes and the differentiation of basic structures. In humans, this includes the period from the time of fertilization to the end of the eighth week after fertilization.
• Tree numbers
  • E05.313
• Qualifiers
  economics, ethics, history, legislation & jurisprudence

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