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Products_type
Antibody
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Products_short_name
[SELP / P-Selectin / CD62P]
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Products_name_syn
[Anti-SELP / P-Selectin / CD62P Antibody (clone Psel.KO.2.5) IHC-plus; SELP; CD62P; CD62; GMP-140; GMRP; Granule membrane protein 140; LECAM3; P-selectin; PSEL; CD62P antigen; GMP140; Granulocyte membrane protein; GRMP; PADGEM; Human SELP; P-Selectin; CD62P]
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Other_names
[P-selectin; P-selectin; P-selectin; GMP-140; granule membrane protein 140; granulocyte membrane protein; CD62 antigen-like family member P; platelet alpha-granule membrane protein; leukocyte-endothelial cell adhesion molecule 3; platelet activation dependent granule-external membrane protein; selectin P (granule membrane protein 140kDa, antigen CD62); CD62 antigen-like family member P; Granule membrane protein 140; GMP-140; Leukocyte-endothelial cell adhesion molecule 3; LECAM3; Platelet activation dependent granule-external membrane protein; PADGEM; CD_antigen: CD62P]
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Products_gene_name
[SELP]
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Other_gene_names
[SELP; SELP; CD62; GRMP; PSEL; CD62P; GMP140; LECAM3; PADGEM; GMRP; GRMP; GMP-140; LECAM3; PADGEM]
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Clonality
Monoclonal
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Clone
[Psel.KO.2.5]
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Reactivity
Human
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Specificity
Recognizes the CD62P cell surface antigen, a 140kD glycoprotein also known as P-selectin. CD62P is expressed by activated platelets and endothelial cells, and plays an important role in adhesive processes between leucocytes and endothelial cells. To produce this mAb, P-selectin-deficient mice were immunized with a pre-B-cell line transfected with human P-selectin cDNA.
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Purity
Affinity Purified
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Form
PBS, pH 7.4, 0.09% sodium azide. Sourced in TCS.
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Concentration
1 mg/ml
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Storage_stability
+4 degree C or -20 degree C, Avoid repeated freezing and thawing.
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Tested_application
Immunohistochemistry (IHC - Paraffin), Immunoprecipitation (IP), Flow Cytometry (FC/FACS)
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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About
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus
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Gene target
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Gene symbol
SELP, SELENOP
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Short name
Mouse Monoclonal [clone Psel KO 2 5] (IgG1) SELP / P-Selectin / CD62P
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Technique
Mouse monoclonal, Mouse, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
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Host
Mouse, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
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Isotype
IgG1, IgG1
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Species
Human, Humans, Mouses
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Alternative name
Mouse monoclonal [clonality Psel.KO.2.5] (IgG1) to H. sapiens selectin P (granule membrane protein 140kDa, antigen CD62) / P-Selectin / CD62P
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Alternative technique
murine
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Alternative to gene target
selectin P (granule membrane protein 140kDa, antigen CD62), CD62 and CD62P and GMP140 and GRMP and LECAM3 and PADGEM and PSEL, SELP and IDBG-104675 and ENSG00000174175 and 6403, oli this GO saccharide binding, nuclei, Selp and IDBG-202346 and ENSMUSG00000026580 and 20344, SELP and IDBG-631778 and ENSBTAG00000020755 and 281486
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Clone name
Psel
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