Monocyte Chemotactic Activating Factor (MCP-1/MCAF)

Products_type

ELISA Kit
Products_short_name

[Monocyte Chemotactic Activating Factor]
Other_names

[MBD1-containing chromatin associated factor; Activating transcription factor 7-interacting protein 1; activating transcription factor 7-interacting protein 1; ATF-interacting protein; ATF7-interacting protein; ATFa-associated modulator; MBD1-containing chromatin-associated factor 1; activating transcription factor 7 interacting protein; ATF-interacting protein; ATF-IP; ATF7-interacting protein; ATFa-associated modulator; hAM; MBD1-containing chromatin-associated factor 1; P621]
Products_gene_name

[MCP-1/MCAF]
Other_gene_names

[ATF7IP; ATF7IP; AM; MCAF; p621; MCAF1; ATF-IP]
Specificity

This sandwich ELISA recognises both natural and recombinant human MCAF. This kit exhibits no detectable cross-reactivity with human; EPO, FGF, GM-CSF, IL-8, IL-1beta, MCP-3, M-CSF, RANTES, SAA, TGF-alpha, TGF-beta, and TNF-alpha.
Description

Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.

Gene target

Monocyte Chemotactic Activating Factor MCP-1/MCAF
Gene symbol

CCL2, CAPG, CCL13, CCL8, SLC25A33, CD46, CCR2, CCL7, IGHVII-1-1, MIR1-1
Short name

Monocyte Chemotactic Activating Factor (MCP-1/MCAF)
Alternative name

Monocyte Chemotactic Activating Factor (MCP-1/MCAF)

Identity

HGNC:10618
Gene

CCL2
Long gene name

C-C motif chemokine ligand 2
Synonyms gene
- SCYA2
Synonyms gene name
- small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je)
- chemokine (C-C motif) ligand 2
Synonyms
- MCP1
- MCP-1
- MCAF
- SMC-CF
- GDCF-2
- HC11
- MGC9434
Synonyms name
GenBank acession
- BC009716
Locus

17q12
Discovery year

1990-07-05
Entrez gene record

6347
Pubmed identfication
- 2004761
RefSeq identity
- NM_002982
Classification
- Chemokine ligands
VEGA ID

OTTHUMG00000132887

Identity

HGNC:10611
Gene

CCL13
Long gene name

C-C motif chemokine ligand 13
Synonyms gene
- SCYA13
Synonyms gene name
- small inducible cytokine subfamily A (Cys-Cys), member 13
- chemokine (C-C motif) ligand 13
Synonyms
- MCP-4
- NCC-1
- SCYL1
- CKb10
- MGC17134
GenBank acession
- AJ001634
Locus

17q12
Discovery year

1997-02-11
Entrez gene record

6357
Pubmed identfication
- 8661057
RefSeq identity
- NM_005408
Classification
- Chemokine ligands
VEGA ID

OTTHUMG00000132890

Identity

HGNC:10635
Gene

CCL8
Long gene name

C-C motif chemokine ligand 8
Synonyms gene
- SCYA8
Synonyms gene name
- small inducible cytokine subfamily A (Cys-Cys), member 8 (monocyte chemotactic protein 2)
- chemokine (C-C motif) ligand 8
Synonyms
- MCP-2
- HC14
GenBank acession
- X99886
Locus

17q12
Discovery year

1996-11-14
Entrez gene record

6355
Pubmed identfication
- 9119400
RefSeq identity
- NM_005623
Classification
- Chemokine ligands
VEGA ID

OTTHUMG00000132883

Identity

HGNC:29681
Gene

SLC25A33
Long gene name

solute carrier family 25 member 33
Synonyms gene name
- solute carrier family 25, member 33
- solute carrier family 25 (pyrimidine nucleotide carrier), member 33
Synonyms
- MGC4399
- BMSC-MCP
- PNC1
GenBank acession
- AF495714
Locus

1p36.22
Discovery year

2006-09-21
Entrez gene record

84275
Pubmed identfication
- 14715278
- 16949250
RefSeq identity
- NM_032315
Classification
- Solute carriers
VEGA ID

OTTHUMG00000001322

Identity

HGNC:6953
Gene

CD46
Long gene name

CD46 molecule
Synonyms gene
- MIC10
- MCP
Synonyms gene name
- antigen identified by monoclonal antibody TRA-2-10
- membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen)
- CD46 antigen, complement regulatory protein
- CD46 molecule, complement regulatory protein
Synonyms
- TRA2.10
- MGC26544
- TLX
GenBank acession
- BC030594
Locus

1q32.2
Discovery year

1988-08-31
Entrez gene record

4179
Pubmed identfication
- 7929741
RefSeq identity
- NM_172361
Classification
- Sushi domain containing
- Complement system regulators and receptors
- CD molecules
VEGA ID

OTTHUMG00000036397
Locus Specific Databases
- LRG_155

Identity

HGNC:10634
Gene

CCL7
Long gene name

C-C motif chemokine ligand 7
Synonyms gene
- SCYA6
- SCYA7
Synonyms gene name
- small inducible cytokine A7 (monocyte chemotactic protein 3)
- chemokine (C-C motif) ligand 7
Synonyms
- MCP-3
- NC28
- FIC
- MARC
- MCP3
Synonyms name
- monocyte chemoattractant protein 3
- monocyte chemotactic protein 3
GenBank acession
- AF043338
Locus

17q12
Discovery year

1993-11-04
Entrez gene record

6354
Pubmed identfication
- 8461011
RefSeq identity
- NM_006273
Classification
- Chemokine ligands
VEGA ID

OTTHUMG00000132889

Identity

HGNC:5670
Gene

IGHVII-1-1
Long gene name

immunoglobulin heavy variable (II)-1-1 (pseudogene)
Synonyms gene name
- immunoglobulin heavy variable (II)-1-1
- immunoglobulin heavy variable (II)-1-1 pseudogene
Synonyms
- IGHV(II)-1-1
GenBank acession
- AB019441
Locus

14q32.33
Discovery year

2000-04-17
Entrez gene record

28377
RefSeq identity
- NG_001019
Classification
- Immunoglobulin heavy locus at 14q32.33
VEGA ID

OTTHUMG00000152325