LOX-1, Soluble form (CLEC8A, hLOX-1, Lectin-like oxidized LDL receptor 1, Lectin-like oxLDL receptor 1, Lectin-type oxidized LDL receptor 1, LOX1, LOX-1, oxidised low density lipoprotein (lectin-like) receptor 1, Oxidized low-density lipoprotein receptor

• Catalog number
  MBS607167
• Price
  Please ask
• Size
  5x1 mg

• Products_type
  Antibody
• Products_short_name
  [LOX-1, Soluble form]
• Products_name_syn
  [Anti -LOX-1, Soluble form (CLEC8A, hLOX-1, Lectin-like oxidized LDL receptor 1, Lectin-like oxLDL receptor 1, Lectin-type oxidized LDL receptor 1, LOX1, LOX-1, oxidised low density lipoprotein (lectin-like) receptor 1, Oxidized low-density lipoprotein receptor]
• Other_names
  [lectin-like oxidized low-density lipoprotein receptor; Oxidized low-density lipoprotein receptor 1; oxidized low-density lipoprotein receptor 1; ox-LDL receptor 1; lectin-like oxLDL receptor 1; lectin-like oxidized LDL receptor 1; lectin-type oxidized LDL receptor 1; lectin-like oxidized low-density lipoprotein receptor; Lectin-like oxidized low-density lipoprotein receptor-1; oxidised low density lipoprotein (lectin-like) receptor 1; oxidized low density lipoprotein (lectin-like) receptor 1; Lectin-like oxidized LDL receptor 1; LOX-1; Lectin-like oxLDL receptor 1; Lectin-type oxidized LDL receptor 1]
• Other_gene_names
  [Olr1; Olr1; LOX-1; Oldr1; Oldlr1; Lox1; Oldlr1; Ox-LDL receptor 1; LOX-1]
• Clonality
  Monoclonal
• Clone
  [9L455]
• Reactivity
  Human
• Specificity
  Recognizes human recombinant LOX-158-273.
• Purity
  Affinity Purified Purified by Protein A affinity chromatography.
• Form
  Supplied as a liquid in PBS, pH 7.4, 0.1% sodium azide.
• Storage_stability
  May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
• Tested_application
  ELISA (EL/EIA), Western Blot (WB)
• Description
  High and low density proteins are supplied by MyBioSource in volumes of 1. Other densities are possible. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  LOX-1   Soluble   form   CLEC8A   hLOX-1   Lectin-like   oxidized   LDL   receptor   Lectin-like   oxLDL   receptor   Lectin   oxidized   LDL   receptor   LOX1   LOX-1   oxidised   lipoprotein   lectin-like   receptor   Oxidized   lipoprotein   receptor  
• Gene symbol
  OLR1, LOX, ALOX15, ALOX5, ALOX12B, PLA2G7, ALOX12, ALOX15B, ALOXE3, IGHVII-1-1
• Short name
  LOX-1, Soluble form (CLEC8A, hLOX-1, Lectin-like oxidized LDL receptor 1, Lectin-like oxLDL receptor 1, Lectin- oxidized LDL receptor 1, LOX1, LOX-1, oxidised lipoprotein (lectin-like) receptor 1, Oxidized - lipoprotein receptor
• Host
  Mouse
• Isotype
  IgG2a
• Alternative name
  LOX-1, Soluble form (CLEC8A, hLOX-1, Lectin-like oxidized LDL receptor 1, Lectin-like oxLDL receptor 1, Lectin-classification oxidized LDL receptor 1, LOX1, LOX-1, oxidised low density lipoprotein (lectin-like) receptor 1, Oxidized low-density lipoprotein receptor

Gene info

• Identity
  HGNC:8133
• Gene
  OLR1
• Long gene name
  oxidized low density lipoprotein receptor 1
• Synonyms gene name
  • oxidised low density lipoprotein (lectin-like) receptor 1
• Synonyms
  • LOX-1
  • SCARE1
  • CLEC8A
• GenBank acession
  • D89050
• Locus
  12p13.2
• Discovery year
  1998-01-16
• Entrez gene record
  4973
• Pubmed identfication
  • 9763655
• RefSeq identity
  • NM_002543
• Classification
  • C-type lectin domain containing
  • Scavenger receptors
• VEGA ID
  OTTHUMG00000168527

Gene info

• Identity
  HGNC:6664
• Gene
  LOX
• Long gene name
  lysyl oxidase
• Synonyms name
  • protein-lysine 6-oxidase
• Locus
  5q23.1
• Discovery year
  1986-01-01
• Entrez gene record
  4015
• Pubmed identfication
  • 1685472
• VEGA ID
  OTTHUMG00000128914
• Locus Specific Databases
  • ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database

Gene info

• Identity
  HGNC:433
• Gene
  ALOX15
• Long gene name
  arachidonate 15-lipoxygenase
• Synonyms
  • 15-LOX-1
• GenBank acession
  • M23892
• Locus
  17p13.2
• Discovery year
  1992-11-20
• Entrez gene record
  246
• Pubmed identfication
  • 1570320
• Classification
  • Arachidonate lipoxygenases
• VEGA ID
  OTTHUMG00000090746

Gene info

• Identity
  HGNC:435
• Gene
  ALOX5
• Long gene name
  arachidonate 5-lipoxygenase
• Synonyms
  • 5-LOX
• GenBank acession
  • J03571
• Locus
  10q11.21
• Discovery year
  1992-07-10
• Entrez gene record
  240
• Pubmed identfication
  • 2565035
• Classification
  • Arachidonate lipoxygenases
• VEGA ID
  OTTHUMG00000018081

Gene info

• Identity
  HGNC:430
• Gene
  ALOX12B
• Long gene name
  arachidonate 12-lipoxygenase, 12R type
• Synonyms
  • 12R-LOX
• Synonyms name
  • 12R-lipoxygenase
• GenBank acession
  • AF038461
• Locus
  17p13.1
• Discovery year
  1998-07-22
• Entrez gene record
  242
• Pubmed identfication
  • 9618483
• Classification
  • Arachidonate lipoxygenases
• VEGA ID
  OTTHUMG00000108180
• Locus Specific Databases
  • LRG_1264

Gene info

• Identity
  HGNC:9040
• Gene
  PLA2G7
• Long gene name
  phospholipase A2 group VII
• Synonyms gene name
  • phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
• Synonyms
  • PAFAH
  • LDL-PLA2
• GenBank acession
  • U20157
• Locus
  6p12.3
• Discovery year
  1999-09-20
• Entrez gene record
  7941
• Pubmed identfication
  • 7700381
  • 8624782
• Classification
  • Phospholipases
• VEGA ID
  OTTHUMG00000014789

Gene info

• Identity
  HGNC:429
• Gene
  ALOX12
• Long gene name
  arachidonate 12-lipoxygenase, 12S type
• Synonyms gene name
  • arachidonate 12-lipoxygenase
• Synonyms
  • 12S-LOX
• Synonyms name
  • platelet 12-LOX
  • Arachidonate 12-lipoxygenase, 12S-type
• GenBank acession
  • M35418
• Locus
  17p13.1
• Discovery year
  1991-08-07
• Entrez gene record
  239
• Pubmed identfication
  • 1570320
• Classification
  • Arachidonate lipoxygenases
• VEGA ID
  OTTHUMG00000102088

Gene info

• Identity
  HGNC:434
• Gene
  ALOX15B
• Long gene name
  arachidonate 15-lipoxygenase type B
• Synonyms gene name
  • arachidonate 15-lipoxygenase, second type
• Synonyms
  • 15-LOX-2
• GenBank acession
  • U78294
• Locus
  17p13.1
• Discovery year
  1998-07-22
• Entrez gene record
  247
• Pubmed identfication
  • 9177185
• Classification
  • Arachidonate lipoxygenases
• VEGA ID
  OTTHUMG00000108181

Gene info

• Identity
  HGNC:13743
• Gene
  ALOXE3
• Long gene name
  arachidonate lipoxygenase 3
• Synonyms
  • eLOX3
  • E-LOX
• Synonyms name
  • Epidermal lipoxygenase-3
  • hydroperoxide isomerase
• GenBank acession
  • AJ269499
• Locus
  17p13.1
• Discovery year
  2000-11-29
• Entrez gene record
  59344
• Pubmed identfication
  • 12881489
• Classification
  • Arachidonate lipoxygenases
• VEGA ID
  OTTHUMG00000108179

Gene info

• Identity
  HGNC:5670
• Gene
  IGHVII-1-1
• Long gene name
  immunoglobulin heavy variable (II)-1-1 (pseudogene)
• Synonyms gene name
  • immunoglobulin heavy variable (II)-1-1
  • immunoglobulin heavy variable (II)-1-1 pseudogene
• Synonyms
  • IGHV(II)-1-1
• GenBank acession
  • AB019441
• Locus
  14q32.33
• Discovery year
  2000-04-17
• Entrez gene record
  28377
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000152325

MeSH Data

• Name
  Cloning, Molecular
• Concept
  Scope note: The insertion of recombinant DNA molecules from prokaryotic and/or eukaryotic sources into a replicating vehicle, such as a plasmid or virus vector, and the introduction of the resultant hybrid molecules into recipient cells without altering the viability of those cells.
• Tree numbers
  • E05.393.220
• Qualifiers
  drug effects, methods, radiation effects

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