LDLR (Low-density Lipoprotein Receptor, LDL Receptor) (PE)

• Catalog number
  MBS609177
• Price
  Please ask
• Size
  5x100 Tests

• Products_type
  Antibody
• Products_short_name
  [LDLR]
• Products_name_syn
  [Anti -LDLR (Low-density Lipoprotein Receptor, LDL Receptor) (PE)]
• Other_names
  [low-density lipoprotein receptor isoform 1; Low-density lipoprotein receptor; low-density lipoprotein receptor; LDL receptor; low-density lipoprotein receptor class A domain-containing protein 3; low density lipoprotein receptor]
• Other_gene_names
  [LDLR; LDLR; FH; FHC; LDLCQ2; LDL receptor]
• Clonality
  Monoclonal
• Clone
  [11C32]
• Reactivity
  Human
• Specificity
  Recognizes human LDLR.
• Purity
  Purified by Protein G affinity chromatography form hybridoma culture supernatant.
• Form
  Supplied as a liquid in saline, 0.5% BSA, 0.09% sodium azide. Labeled with R-Phycoerythrin (PE).
• Concentration
  0.025 mg/mL
• Storage_stability
  Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
• Tested_application
  Flow Cytometry (FC/FACS)
• Description
  High and low density proteins are supplied by MyBioSource in volumes of 1. Other densities are possible. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  LDLR   Lipoprotein   Receptor   LDL   Receptor  
• Gene symbol
  LDLR, LDLR-AS1, PLA2G7
• Short name
  LDLR ( - Lipoprotein Receptor, LDL Receptor) (PE)
• Host
  Mouse
• Isotype
  IgG1
• Label
  PE
• Alternative name
  low density lipoprotein receptor (Low-density Lipoprotein Receptor, LDL Receptor) (peroxidase)
• Alternative to gene target
  low density lipoprotein receptor, FH and FHC and LDLCQ2, LDLR and IDBG-28808 and ENSG00000130164 and 3949, very-low-density lipoprotein particle receptor activity, Cell surfaces, Ldlr and IDBG-141358 and ENSMUSG00000032193 and 16835, LDLR and IDBG-643476 and ENSBTAG00000012314 and 281276

Gene info

• Identity
  HGNC:6547
• Gene
  LDLR
• Long gene name
  low density lipoprotein receptor
• Synonyms
  • LDLCQ2
• Synonyms name
  • familial hypercholesterolemia
• GenBank acession
  • AY114155
• Locus
  19p13.2
• Discovery year
  1986-01-01
• Entrez gene record
  3949
• Classification
  • Low density lipoprotein receptors
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000171935
• Locus Specific Databases
  • UCL LDLR-LOVD, British Heart Foundation variant database
  • UMD Locus Specific Databases
  • LRG_274

Gene info

• Identity
  HGNC:54407
• Gene
  LDLR-AS1
• Long gene name
  LDLR antisense RNA 1
• Synonyms
  • BM450697
• Locus
  19p13.2
• Discovery year
  2019-08-08
• Entrez gene record
  115271120
• Pubmed identfication
  • 31279228
• RefSeq identity
  • NR_163945
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:9040
• Gene
  PLA2G7
• Long gene name
  phospholipase A2 group VII
• Synonyms gene name
  • phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
• Synonyms
  • PAFAH
  • LDL-PLA2
• GenBank acession
  • U20157
• Locus
  6p12.3
• Discovery year
  1999-09-20
• Entrez gene record
  7941
• Pubmed identfication
  • 7700381
  • 8624782
• Classification
  • Phospholipases
• VEGA ID
  OTTHUMG00000014789

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