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Products_type
Antibody
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Products_short_name
[Integrin, beta1]
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Products_name_syn
[Anti -Integrin, beta1 (CD29, Very Late Antigen, VLAb1, Platelet gplla, ITGB1, Fibrinogen Receptor beta Subunit, FNRB, Integrin VLA4 Subunit beta, MDF2, MSK12, Very Late Activation Protein beta Polypeptide, VLAB, VLAbeta) (PE)]
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Other_names
[integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12); Integrin, beta 1 (Fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12); integrin beta-1; OTTHUMP00000019420; integrin VLA-4 beta subunit; very late activation protein, beta polypeptide; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)]
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Other_gene_names
[ITGB1; ITGB1; CD29; FNRB; MDF2; VLAB; GPIIA; MSK12; VLA-BETA]
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Clonality
Monoclonal
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Clone
[10B1285]
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Reactivity
Mouse, Rat
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Specificity
Recognizes the murine integrin beta 1 subunit. Inhibits beta 1 integrin mediated adhesion. Species Crossreactivity: rat.
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Purity
Affinity Purified Purified by Protein G affinity chromatography.
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Form
Supplied as a lyophilized powder from PBS, pH 7.4, 1% BSA, 0.09% sodium azide. Labeled with R-Phycoerythrin (PE). Reconstitute with 1ml sterile 40-50% glycerol, ddH2O.
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Storage_stability
May be stored at 4 degree C before opening. DO NOT FREEZE! Stable at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 12 months at 4 degree C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light.
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Tested_application
Flow Cytometry (FC/FACS)
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Description
Antigens are peptides or recombinant or native dependent on the production method. Platelets, also called thrombocytes or cloth cells in blood and are needed to stop bleeding by clumping and clotting the blood the vessels when the an injury occurs. Teh bone marrow will produce the platelets that have no nucleus. Platelates are unique to mammals, the are curved shaped 1900nm to 3100 nm large nucleus free clothing structures. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbol
ITGB1, ITGB1-DT, IATPR
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Short name
Integrin, beta1 (CD29, Very Late Antigen, VLAb1, Platelet gplla, ITGB1, Fibrinogen Receptor beta Subunit, FNRB, Integrin VLA4 Subunit beta, MDF2, MSK12, Very Late Activation Protein beta Polypeptide, VLAB, VLAbeta) (PE)
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Technique
activation, antigen, antigenes
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Host
Hamster
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Isotype
IgG
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Label
PE
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Alternative name
Integrin, beta1 (CD29, Very Late protein, VLAb1, Platelet gplla, integrin, b 1 (fibronectin receptor, b polypeptide, antigen CD29 includes MDF2, MSK12), Fibrinogen Receptor b functionnal sequence, FNRB, Integrin VLA4 functionnal sequence b, MDF2, MSK12, Very Late Activation Protein b multipeptide, VLAB, VLAbeta) (peroxidase)
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Alternative technique
antigenes
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Alternative to gene target
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12), CD29 and FNRB and GPIIA and MDF2 and MSK12 and VLA-BETA and VLAB, ITGB1 and IDBG-68302 and ENSG00000150093 and 3688, alpha-actinin binding, Cell surfaces, Itgb1 and IDBG-201159 and ENSMUSG00000025809 and 16412, ITGB1 and IDBG-637396 and ENSBTAG00000015910 and 281876
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