Human Fas Receptor

• Catalog number
  MBS695806
• Price
  Please ask
• Size
  1 mg

• Products_type
  Active Protein
• Products_short_name
  [Fas Receptor]
• Products_name_syn
  [Recombinant Human sFas Receptor]
• Other_names
  [Tumor necrosis factor receptor superfamily member 6; Tumor necrosis factor receptor superfamily member 6; tumor necrosis factor receptor superfamily member 6; Fas AMA; FAS 827dupA; CD95 antigen; FASLG receptor; apoptosis antigen 1; Delta Fas/APO-1/CD95; FAS receptor variant 9; APO-1 cell surface antigen; TNF receptor superfamily member 6; apoptosis-mediating surface antigen FAS; Fas (TNF receptor superfamily, member 6); tumor necrosis factor receptor superfamily, member 6; Fas cell surface death receptor; Apo-1 antigen; Apoptosis-mediating surface antigen FAS; FASLG receptor; CD_antigen: CD95]
• Products_gene_name
  [sFas]
• Other_gene_names
  [FAS; FAS; APT1; CD95; FAS1; APO-1; FASTM; ALPS1A; TNFRSF6; APT1; FAS1; TNFRSF6]
• Reactivity
  Species Reactivity: Human
• Purity
  Above 98% as determined by SDS-PAGE Analysis.
• Storage_stability
  At -20 degree C
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  Fas   Receptor  
• Gene symbol
  FAS, FADD, PTPN13
• Short name
  Fas Receptor
• Host
  E Coli
• Species
  Human, Humans
• Alternative name
  H. sapiens Fas (tumor necrosis factor receptor superfamily, member 6) Receptor
• Alternative to gene target
  Fas (TNF receptor superfamily, member 6), ALPS1A and APO-1 and APT1 and CD95 and FAS1 and FASTM and TNFRSF6, FAS and IDBG-81669 and ENSG00000026103 and 355, identical protein binding, nuclei, Fas and IDBG-159577 and ENSMUSG00000024778 and 14102, FAS and IDBG-637356 and ENSBTAG00000010785 and 282488

Gene info

• Identity
  HGNC:11920
• Gene
  FAS
• Long gene name
  Fas cell surface death receptor
• Synonyms gene
  • FAS1
  • APT1
  • TNFRSF6
• Synonyms gene name
  • tumor necrosis factor receptor superfamily, member 6
  • Fas (TNF receptor superfamily, member 6)
• Synonyms
  • CD95
  • APO-1
• Synonyms name
  • TNF receptor superfamily member 6
• GenBank acession
  • M67454
• Locus
  10q23.31
• Discovery year
  1992-06-25
• Entrez gene record
  355
• Pubmed identfication
  • 1385299
  • 1385309
• Classification
  • Tumor necrosis factor receptor superfamily
  • Death inducing signaling complex
  • CD molecules
• VEGA ID
  OTTHUMG00000018701
• Locus Specific Databases
  • Autoimmune Lymphoproliferative Syndrome Database (ALPSbase): Database of mutations causing human ALPS
  • LOVD at NCBI
  • LRG_134

Gene info

• Identity
  HGNC:3573
• Gene
  FADD
• Long gene name
  Fas associated via death domain
• Synonyms gene name
  • Fas (TNFRSF6)-associated via death domain
• Synonyms
  • MORT1
  • GIG3
• Synonyms name
  • Fas-associating protein with death domain
  • Fas-associating death domain-containing protein
  • mediator of receptor-induced toxicity
  • growth-inhibiting gene 3 protein
• GenBank acession
  • U24231
• Locus
  11q13.3
• Discovery year
  1999-05-07
• Entrez gene record
  8772
• Pubmed identfication
  • 7536190
  • 7538907
• RefSeq identity
  • NM_003824
• Classification
  • Death effector domain containing
  • Death inducing signaling complex
  • Ripoptosome
• VEGA ID
  OTTHUMG00000167264
• Locus Specific Databases
  • LRG_228

Gene info

• Identity
  HGNC:9646
• Gene
  PTPN13
• Long gene name
  protein tyrosine phosphatase non-receptor type 13
• Synonyms gene name
  • protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
• Synonyms
  • PTP1E
  • PTP-BAS
  • PTPL1
  • PTP-BL
• Synonyms name
  • APO-1/CD95 (Fas)-associated phosphatase
• Locus
  4q21.3
• Discovery year
  1995-02-17
• Pubmed identfication
  • 8287977
• Classification
  • Protein tyrosine phosphatases non-receptor type
  • PDZ domain containing
  • FERM domain containing
• VEGA ID
  OTTHUMG00000160968

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