CHUK, CT (CHUK, IKKA, TCF16, Inhibitor of nuclear factor kappa-B kinase subunit alpha, Conserved helix-loop-helix ubiquitous kinase, I-kappa-B kinase 1, Nuclear factor NF-kappa-B inhibitor kinase alpha, Transcription factor 16)
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Catalog numberMBS647770
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Price:
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Size5x0.2 mL
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Products_typeAntibody
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Products_short_name[CHUK]
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Products_name_syn[Anti -CHUK, CT (CHUK, IKKA, TCF16, Inhibitor of nuclear factor kappa-B kinase subunit alpha, Conserved helix-loop-helix ubiquitous kinase, I-kappa-B kinase 1, Nuclear factor NF-kappa-B inhibitor kinase alpha, Transcription factor 16)]
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Other_names[CHUK, partial; Inhibitor of nuclear factor kappa-B kinase subunit alpha; inhibitor of nuclear factor kappa-B kinase subunit alpha; TCF-16; IKK-a kinase; I-kappa-B kinase 1; I-kappa-B kinase-alpha; transcription factor 16; IkB kinase alpha subunit; Nuclear factor NFkappaB inhibitor kinase alpha; conserved helix-loop-helix ubiquitous kinase; Conserved helix-loop-helix ubiquitous kinase; I-kappa-B kinase 1; IKK1; Nuclear factor NF-kappa-B inhibitor kinase alpha; NFKBIKA; Transcription factor 16]
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Other_gene_names[CHUK; CHUK; IKK1; IKKA; IKBKA; TCF16; NFKBIKA; IKK-alpha; IKKA; TCF16; I-kappa-B kinase alpha; IKK-A; IKK-alpha; IkBKA; IkappaB kinase; IKK1; NFKBIKA; TCF-16]
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ClonalityPolyclonal
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ReactivityHuman
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SpecificityHuman
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PurityAffinity Purified Purified by Protein A affinity chromatography.
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FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
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Storage_stabilityMay be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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Tested_applicationELISA (EL/EIA), Western Blot (WB)
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DescriptionThe CHUK, CT (CHUK, IKKA, TCF16, Inhibitor of factor kappa-B kinase subunit alpha, Conserved helix-loop-helix ubiquitous kinase, I-kappa-B kinase 1, factor NF-kappa-B inhibitor kinase alpha, Transcription factor 16) is a α- or alpha protein sometimes glycoprotein present in blood. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme. The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
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Gene target
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Gene symbolCHUK, CHUK-DT, NFE4, NFE2, NEFH, NFKB1, INA, NFASC, NFATC1, NFYC
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Short nameCHUK, CT (CHUK, IKKA, TCF16, Inhibitor of factor kappa-B kinase subunit alpha, Conserved helix-loop-helix ubiquitous kinase, I-kappa-B kinase 1, factor NF-kappa-B inhibitor kinase alpha, Transcription factor 16)
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HostRabbit
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IsotypeIgG
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Alternative nameconserved helix-loop-helix ubiquitous kinase, CT (conserved helix-loop-helix ubiquitous kinase, IKKA, TCF16, suppressor on nuclear factor kappa-B phosphorylation catalyst functionnal sequence a, Conserved helix-loop-helix ubiquitous phosphorylation catalyst, I-kappa-B phosphorylation catalyst 1, Nuclear factor NF-kappa-B suppressor phosphorylation catalyst a, Transcription factor 16)
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Alternative to gene targetconserved helix-loop-helix ubiquitous kinase, IKBKA and IKK-alpha and IKK1 and IKKA and NFKBIKA and TCF16, CHUK and IDBG-243385 and ENSG00000213341 and 1147, transferase activity, nuclei, Chuk and IDBG-169132 and ENSMUSG00000025199 and 12675, CHUK and IDBG-638708 and ENSBTAG00000007591 and 281073
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Gene info
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Identity
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Gene
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Long gene namecomponent of inhibitor of nuclear factor kappa B kinase complex
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Synonyms gene
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Synonyms gene name
- conserved helix-loop-helix ubiquitous kinase
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1995-03-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- I kappa B kinases
- IKK complex
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameCHUK divergent transcript
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Locus
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Discovery year2021-07-30
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Classification
- Divergent transcripts
Gene info
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Identity
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Gene
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Long gene namenuclear factor, erythroid 4
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Synonyms
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Locus
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Discovery year2013-08-23
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namenuclear factor, erythroid 2
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Synonyms gene name
- nuclear factor (erythroid-derived 2), 45kD
- nuclear factor (erythroid-derived 2), 45kDa
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Synonyms
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GenBank acession
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Locus
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Discovery year1993-11-03
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Basic leucine zipper proteins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameneurofilament heavy chain
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Synonyms gene name
- neurofilament, heavy polypeptide 200kDa
- neurofilament heavy polypeptide
- neurofilament heavy
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Synonyms
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Locus
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Discovery year1988-08-31
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Entrez gene record
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RefSeq identity
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Classification
- Intermediate filaments Type IV
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namenuclear factor kappa B subunit 1
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Synonyms gene name
- nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1991-11-14
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- NF-kappa B complex subunits
- Ankyrin repeat domain containing
- IPT domain containing
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameinternexin neuronal intermediate filament protein alpha
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Synonyms gene
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Synonyms gene name
- internexin neuronal intermediate filament protein, alpha
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-03-24
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Intermediate filaments Type IV
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameneurofascin
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Synonyms gene name
- neurofascin homolog (chicken)
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Synonyms
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GenBank acession
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Locus
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Discovery year2005-11-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Ig-like cell adhesion molecule family
- I-set domain containing
- Fibronectin type III domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namenuclear factor of activated T cells 1
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Synonyms gene name
- nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
- nuclear factor of activated T-cells 1
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Synonyms
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GenBank acession
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Locus
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Discovery year1994-11-16
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Nuclear factors of activated T-cells
- IPT domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namenuclear transcription factor Y subunit gamma
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Synonyms gene name
- nuclear transcription factor Y, gamma
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Synonyms
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GenBank acession
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Locus
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Discovery year1996-10-26
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- MicroRNA protein coding host genes
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VEGA ID