Caspase 2 Substrate 1m (ICH-1) fluorogenic

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Description

Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.

Gene target

Caspase Substrate ICH-1 fluorogenic
Gene symbol

CASP2, CASP4, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1, IGKV1OR2-1, MIR1289-1, MIR101-1, MIR16-1
Short name

Caspase 2 Substrate 1m (ICH-1) fluorogenic
Alternative name

caspase 2 Substrate 1m (ICH-1) fluorogenic

Identity

HGNC:1503
Gene

CASP2
Long gene name

caspase 2
Synonyms gene
- NEDD2
Synonyms gene name
- neural precursor cell expressed, developmentally down-regulated 2
- caspase 2, apoptosis-related cysteine peptidase
Synonyms
- ICH1
- PPP1R57
- MGC2181
Synonyms name
- protein phosphatase 1, regulatory subunit 57
GenBank acession
- AK096245
- BC002427
- BM998653
- BX537669
- CB988674
- U13021
Locus

7q34
Discovery year

1994-01-21
Entrez gene record

835
Pubmed identfication
- 7789948
- 8780721
- 19075813
RefSeq identity
- NM_032982
Classification
- Caspases
- Caspase recruitment domain containing
- Protein phosphatase 1 regulatory subunits
VEGA ID

OTTHUMG00000023641

Identity

HGNC:1505
Gene

CASP4
Long gene name

caspase 4
Synonyms gene name
- caspase 4, apoptosis-related cysteine protease
- caspase 4, apoptosis-related cysteine peptidase
Synonyms
- ICE(rel)II
- ICH-2
- TX
GenBank acession
- U25804
Locus

11q22.3
Discovery year

1996-07-22
Entrez gene record

837
Pubmed identfication
- 7797510
- 9250871
RefSeq identity
- NM_001225
Classification
- Caspases
- Caspase recruitment domain containing
VEGA ID

OTTHUMG00000166078

Identity

HGNC:5670
Gene

IGHVII-1-1
Long gene name

immunoglobulin heavy variable (II)-1-1 (pseudogene)
Synonyms gene name
- immunoglobulin heavy variable (II)-1-1
- immunoglobulin heavy variable (II)-1-1 pseudogene
Synonyms
- IGHV(II)-1-1
GenBank acession
- AB019441
Locus

14q32.33
Discovery year

2000-04-17
Entrez gene record

28377
RefSeq identity
- NG_001019
Classification
- Immunoglobulin heavy locus at 14q32.33
VEGA ID

OTTHUMG00000152325

Identity

HGNC:5760
Gene

IGKV1OR2-1
Long gene name

immunoglobulin kappa variable 1/OR2-1 (pseudogene)
Synonyms gene
- IGKVPZ1
- IGKV1OR-1
Synonyms gene name
- immunoglobulin kappa variable 1/OR-1
- immunoglobulin kappa variable 1/OR-1 pseudogene
- immunoglobulin kappa variable 1/OR-1 (pseudogene)
Synonyms
- IGKV1/OR-1
- IGKV1/OR2-1
GenBank acession
- Z12367
Locus

2p11.1
Discovery year

2000-04-18
Entrez gene record

3531
Pubmed identfication
- 2853098
Classification
- Immunoglobulin kappa (IGK) orphons
VEGA ID

OTTHUMG00000155081

Name

Models, Chemical
Concept

Scope note: Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
Tree numbers
- E05.599.495