Bone Morphogenetic Protein Receptor Type 1B (BMPR-IB, BMPR1B, BR1b, BMP Type-1B Receptor, Receptor-like Kinase 6, ALK6, ALK-6, CDw293) (APC)
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Catalog numberMBS632595
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PricePlease ask
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Size100 Tests
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Products_typeAntibody
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Products_short_name[Bone Morphogenetic Protein Receptor Type 1B]
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Products_name_syn[Anti -Bone Morphogenetic Protein Receptor Type 1B (BMPR-IB, BMPR1B, BR1b, BMP Type-1B Receptor, Receptor-like Kinase 6, ALK6, ALK-6, CDw293) (APC)]
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Other_names[bone morphogenetic protein receptor type-1B isoform b; Bone morphogenetic protein receptor type-1B; bone morphogenetic protein receptor type-1B; BMPR-1B; BMP type-1B receptor; activin receptor-like kinase 6; serine/threonine receptor kinase; bone morphogenetic protein receptor, type IB]
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Other_gene_names[BMPR1B; BMPR1B; ALK6; ALK-6; CDw293; BMP type-1B receptor; BMPR-1B]
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ClonalityMonoclonal
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Clone[11C3]
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ReactivityHuman
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SpecificityRecognizes human BMPR-IB.
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PurityAffinity Purified Purified by Protein G affinity chromatography.
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FormSupplied as a liquid in saline, 0.5% BSA, 0.1% sodium azide. Labeled with Allophycocyanin (APC).
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Storage_stabilityMay be stored at 4 degree C before opening. DO NOT FREEZE! Stable at 4 degree C. Stable for 12 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Freezing Labeled with Allophycocyanin (APC) conjugates will result in a substantial loss of activity. Further dilutions can be made in assay buffer. APC is light sensitive.
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Tested_applicationFlow Cytometry (FC/FACS)
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DescriptionThe receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbolBMPR1B, BMPR1B-DT, BMPR2, ALK, GDF11, GDF10, NT5C1B, ENPP7, APC, BMP1
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Short nameBone Morphogenetic Protein Receptor 1B (BMPR-IB, BMPR1B, BR1b, BMP -1B Receptor, Receptor-like Kinase 6, ALK6, ALK-6, CDw293) (APC)
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HostMouse
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IsotypeIgG2b
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LabelAPC
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Alternative nameBone Morphogenetic Protein Receptor classification 1B (BMPR-IB, bone morphogenetic protein receptor, classification IB, BR1b, BMP classification-1B Receptor, Receptor-like phosphorylation catalyst 6, ALK6, anaplastic lymphoma receptor tyrosine kinase-6, CDw293) (adenomatous polyposis coli)
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Alternative to gene targetbone morphogenetic protein receptor, type IB, ALK-6 and ALK6 and CDw293, BMPR1B and IDBG-30667 and ENSG00000138696 and 658, transforming growth factor beta receptor activity, Plasma membranes, Bmpr1b and IDBG-196928 and ENSMUSG00000052430 and 12167, BMPR1B and IDBG-641011 and ENSBTAG00000002081 and 407128
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Tissuebone
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Gene info
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Identity
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Gene
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Long gene namebone morphogenetic protein receptor type 1B
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Synonyms gene name
- bone morphogenetic protein receptor, type IB
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Synonyms
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GenBank acession
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Locus
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Discovery year1997-03-19
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CD molecules
- Type 1 receptor serine/threonine kinases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameBMPR1B divergent transcript
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Synonyms gene
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Synonyms gene name
- BMPR1B antisense RNA 1 (head to head)
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Synonyms
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Locus
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Discovery year2014-07-14
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Entrez gene record
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Classification
- Divergent transcripts
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namebone morphogenetic protein receptor type 2
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Synonyms gene
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Synonyms gene name
- primary pulmonary hypertension 1
- bone morphogenetic protein receptor, type II (serine/threonine kinase)
- bone morphogenetic protein receptor type II
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Synonyms
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GenBank acession
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Locus
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Discovery year1997-03-19
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Type 2 receptor serine/threonine kinases
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameALK receptor tyrosine kinase
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Synonyms gene name
- anaplastic lymphoma kinase (Ki-1)
- anaplastic lymphoma receptor tyrosine kinase
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Synonyms
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GenBank acession
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Locus
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Discovery year1993-08-24
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Receptor tyrosine kinases
- CD molecules
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namegrowth differentiation factor 11
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-12-02
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Entrez gene record
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Pubmed identfication
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Classification
- Transforming growth factor beta superfamily
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namegrowth differentiation factor 10
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Synonyms
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GenBank acession
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Locus
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Discovery year1997-09-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Transforming growth factor beta superfamily
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name5'-nucleotidase, cytosolic IB
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-04-18
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Entrez gene record
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Pubmed identfication
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Classification
- 5'-nucleotidases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameectonucleotide pyrophosphatase/phosphodiesterase 7
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2004-04-29
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Ectonucleotide pyrophosphatase/phosphodiesterase family
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameAPC regulator of WNT signaling pathway
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Synonyms gene name
- adenomatosis polyposis coli
- adenomatous polyposis coli
- APC, WNT signaling pathway regulator
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Protein phosphatase 1 regulatory subunits
- Armadillo repeat containing
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namebone morphogenetic protein 1
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Synonyms gene
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Synonyms gene name
- procollagen C-endopeptidase
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Synonyms
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Synonyms name
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Locus
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Discovery year1990-06-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Bone morphogenetic proteins
- Astacins
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VEGA ID