BACE2, Asp1 (CT) (Beta-site APP Cleaving Enzyme, Aspartyl Protease 2, DRAP, Down Region Aspartic Protease, Memapsin)

  • Catalog number
    MBS617722
  • Price
    Please ask
  • Size
    0.1 mg
  • Products_type
    Antibody
  • Products_short_name
    [BACE2, Asp1]
  • Products_name_syn
    [Anti -BACE2, Asp1 (CT) (Beta-site APP Cleaving Enzyme, Aspartyl Protease 2, DRAP, Down Region Aspartic Protease, Memapsin)]
  • Other_names
    [beta-secretase 2 isoform A preproprotein; Beta-secretase 2; beta-secretase 2; memapsin-1; theta-secretase; aspartyl protease 1; 56 kDa aspartic-like protease; Down syndrome region aspartic protease; transmembrane aspartic proteinase Asp1; membrane-associated aspartic protease 1; beta-site amyloid beta A4 precursor protein-cleaving enzyme 2; beta-site APP-cleaving enzyme 2; Aspartic-like protease 56 kDa; Aspartyl protease 1; ASP1; Asp 1; Beta-site amyloid precursor protein cleaving enzyme 2; Beta-site APP cleaving enzyme 2; Down region aspartic protease; DRAP; Memapsin-1; Membrane-associated aspartic protease 1; Theta-secretase]
  • Other_gene_names
    [BACE2; BACE2; ASP1; BAE2; DRAP; AEPLC; ALP56; ASP21; CDA13; CEAP1; AEPLC; ALP56; ASP21; ASP1; Asp 1; Beta-site APP cleaving enzyme 2; DRAP]
  • Clonality
    Polyclonal
  • Reactivity
    Human, Mouse, Rat
  • Specificity
    Recognizes human BACE2. Species crossreactivity: Mouse and rat.
  • Purity
    Affinity Purified Immunoaffinity chromatography purified IgG
  • Form
    Supplied as a liquid, 100ug in 200ul of PBS, 0.02% sodium azide.
  • Storage_stability
    May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
  • Tested_application
    ELISA (EL/EIA), Western Blot (WB)
  • Description
    Enzymes are cleaving the substrate. If the substrate is DNA they are called restriction enzymes. Activating enzymes will cut off the domain that is biological active to become functional.
  • Gene target
    BACE2   Asp1   Beta-site   APP   Cleaving   Aspartyl   Protease   DRAP   Down   Region   Aspartic   Protease   Memapsin  
  • Gene symbol
    BACE2, APP-DT, APP, PABPC4, BACE2-IT1, NAE1
  • Short name
    BACE2, Asp1 (CT) (Beta-site APP Cleaving Enzyme, Aspartyl Protease 2, DRAP, Down Region Aspartic Protease, Memapsin)
  • Technique
    Enzyme, enzymes
  • Host
    Rabbit
  • Isotype
    IgG
  • Alternative name
    BACE2, Asp1 (CT) (b-site amyloid beta (A4) precursor protein Cleaving Enzyme, Aspartyl Protease 2, DRAP, Down Region Aspartic Protease, Memapsin)
  • Alternative technique
    enzymes
  • Alternative to gene target
    amyloid beta (A4) precursor protein, AAA and ABETA and ABPP and AD1 and APPI and CTFgamma and CVAP and PN-II and PN2, APP and IDBG-1100 and ENSG00000142192 and 351, growth factor receptor binding, nuclei, App and IDBG-172954 and ENSMUSG00000022892 and 11820, APP and IDBG-630293 and ENSBTAG00000017753 and 280722
  • Tissue
    region
Gene info
Gene info
  • Identity
    HGNC:55075
  • Gene
    APP-DT
  • Long gene name
    APP divergent transcript
  • Locus
    21q21.3
  • Discovery year
    2020-06-12
  • Classification
    • Divergent transcripts
Gene info
Gene info
Gene info
  • Identity
    HGNC:16024
  • Gene
    BACE2-IT1
  • Long gene name
    BACE2 intronic transcript 1
  • Synonyms gene
  • Synonyms gene name
    • chromosome 21 open reading frame 75
    • non-protein coding RNA 228
    • BACE2 intronic transcript 1 (non-protein coding)
  • Synonyms
  • Locus
    21q22.2
  • Discovery year
    2002-11-26
  • Entrez gene record
    282569
  • Classification
    • Intronic transcripts
  • VEGA ID
    OTTHUMG00000086745
Gene info
MeSH Data
  • Name
    Gene Knockdown Techniques
  • Concept
    Scope note: The artificial induction of GENE SILENCING by the use of RNA INTERFERENCE to reduce the expression of a specific gene. It includes the use of DOUBLE-STRANDED RNA, such as SMALL INTERFERING RNA and RNA containing HAIRPIN LOOP SEQUENCE, and ANTI-SENSE OLIGONUCLEOTIDES.
  • Tree numbers
    • E05.393.335.500
  • Qualifiers
    ethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data
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BACE2 Asp1 CT) (Beta site APP Cleaving Enzyme Aspartyl Prote
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