ARHGEF6 (COOL2, KIAA0006, PIXA, Rho Guanine Nucleotide Exchange Factor 6, Alpha-Pix, COOL-2, PAK-interacting Exchange Factor alpha, Rac/Cdc42 Guanine Nucleotide Exchange Factor 6)

• Catalog number
  MBS646094
• Price
  Please ask
• Size
  5x0.1 mg

• Products_type
  Antibody
• Products_short_name
  [ARHGEF6]
• Products_name_syn
  [Anti -ARHGEF6 (COOL2, KIAA0006, PIXA, Rho Guanine Nucleotide Exchange Factor 6, Alpha-Pix, COOL-2, PAK-interacting Exchange Factor alpha, Rac/Cdc42 Guanine Nucleotide Exchange Factor 6)]
• Other_names
  [ARHGEF6 protein; Rho guanine nucleotide exchange factor 6; rho guanine nucleotide exchange factor 6; PAK-interacting exchange factor alpha; PAK-interacting exchange factor, alpha; Rac/Cdc42 guanine exchange factor (GEF) 6; rac/Cdc42 guanine nucleotide exchange factor 6; Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6; Alpha-Pix; COOL-2; PAK-interacting exchange factor alpha; Rac/Cdc42 guanine nucleotide exchange factor 6]
• Other_gene_names
  [ARHGEF6; ARHGEF6; PIXA; COOL2; MRX46; Cool-2; alphaPIX; alpha-PIX; COOL2; KIAA0006; PIXA]
• Clonality
  Polyclonal
• Reactivity
  Human, Rabbit
• Specificity
  Recognizes human ARHGEF6.
• Purity
  Affinity Purified Purified by Protein A affinity chromatography.
• Form
  Supplied as a liquid in PBS, pH 7.2.
• Storage_stability
  May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Tested_application
  Western Blot (WB)
• Description
  The ARHGEF6 (COOL2, KIAA0006, PIXA, Rho Guanine Nucleotide Exchange Factor 6, Alpha-Pix, COOL-2, PAK-interacting Exchange Factor alpha, Rac/Cdc42 Guanine Nucleotide Exchange Factor 6) is a α- or alpha protein sometimes glycoprotein present in blood. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.

• Gene target
  ARHGEF6   COOL2   KIAA0006   PIXA   Rho   Guanine   Nucleotide   Exchange   Factor   Alpha-Pix   COOL-2   PAK-interacting   Exchange   Factor   alpha   Rac/Cdc42   Guanine   Nucleotide   Exchange   Factor  
• Gene symbol
  ARHGEF6, PKN2, MIR7-2, MIR329-2, MIR512-2, MIR521-2, MIR1289-2, MIR509-2, KRTAP13-2, RNU6-2
• Short name
  ARHGEF6 (COOL2, KIAA0006, PIXA, Rho Guanine Nucleotide Exchange Factor 6, Alpha-Pix, COOL-2, PAK-interacting Exchange Factor alpha, Rac/Cdc42 Guanine Nucleotide Exchange Factor 6)
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  Rac/cellular division cycle 42 (GTP binding protein, 25kDa) guanine nucleotide exchange factor (GEF) 6 (COOL2, KIAA0006, PIXA, Rho Guanine Nucleotide Exchange Factor 6, a-Pix, COOL-2, PAK-interacting Exchange Factor a, Rac/cellular division cycle 42 (GTP binding protein, 25kDa) Guanine Nucleotide Exchange Factor 6)
• Alternative to gene target
  Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6, alpha-PIX and alphaPIX and Cool-2 and COOL2 and MRX46 and PIXA, ARHGEF6 and IDBG-87668 and ENSG00000129675 and 9459, protein binding, Cell surfaces, Arhgef6 and IDBG-147466 and ENSMUSG00000031133 and 73341, ARHGEF6 and IDBG-631282 and ENSBTAG00000017850 and 533823

Gene info

• Identity
  HGNC:685
• Gene
  ARHGEF6
• Long gene name
  Rac/Cdc42 guanine nucleotide exchange factor 6
• Synonyms gene
  • MRX46
• Synonyms gene name
  • mental retardation, X-linked 46
  • Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
• Synonyms
  • alphaPIX
  • Cool-2
  • KIAA0006
  • alpha-PIX
  • Cool2
  • αPix
• Synonyms name
  • Rac/Cdc42 guanine exchange factor (GEF) 6
  • PAK-interacting exchange factor, alpha
  • rho guanine nucleotide exchange factor 6
• GenBank acession
  • D13631
• Locus
  Xq26.3
• Discovery year
  2000-07-27
• Entrez gene record
  9459
• Pubmed identfication
  • 7584048
  • 9659915
• RefSeq identity
  • NM_004840
• Classification
  • Pleckstrin homology domain containing
  • Dbl family Rho GEFs
• VEGA ID
  OTTHUMG00000022518
• Locus Specific Databases
  • Global Variome shared LOVD

Gene info

• Identity
  HGNC:9406
• Gene
  PKN2
• Long gene name
  protein kinase N2
• Synonyms gene
  • PRKCL2
• Synonyms gene name
  • protein kinase C-like 2
• Synonyms
  • PRK2
  • Pak-2
  • STK7
• Synonyms name
  • cardiolipin-activated protein kinase Pak2
• GenBank acession
  • U33052
• Locus
  1p22.2
• Discovery year
  1997-10-10
• Entrez gene record
  5586
• Pubmed identfication
  • 7988719
  • 7851406
• RefSeq identity
  • NM_006256
• Classification
  • C2 domain containing protein kinases
  • AGC family kinases
  • Small nucleolar RNA protein coding host genes
• VEGA ID
  OTTHUMG00000010074

Gene info

• Identity
  HGNC:31639
• Gene
  MIR7-2
• Long gene name
  microRNA 7-2
• Synonyms gene
  • MIRN7-2
• Synonyms
  • hsa-mir-7-2
• Locus
  15q26.1
• Discovery year
  2004-04-23
• Entrez gene record
  407044
• RefSeq identity
  • NR_029606
• Classification
  • MicroRNA MIR7 family

Gene info

• Identity
  HGNC:32051
• Gene
  MIR329-2
• Long gene name
  microRNA 329-2
• Synonyms gene
  • MIRN329-2
• Synonyms
  • hsa-mir-329-2
• Locus
  14q32.31
• Discovery year
  2005-07-11
• Entrez gene record
  574409
• RefSeq identity
  • NR_029968
• Classification
  • MicroRNA MIR329 family

Gene info

• Identity
  HGNC:32091
• Gene
  MIR512-2
• Long gene name
  microRNA 512-2
• Synonyms gene
  • MIRN512-2
• Synonyms
  • hsa-mir-512-2
• Locus
  19q13.42
• Discovery year
  2005-07-15
• Entrez gene record
  574459
• RefSeq identity
  • NR_030181
• Classification
  • MicroRNA MIR506 family

Gene info

• Identity
  HGNC:32113
• Gene
  MIR521-2
• Long gene name
  microRNA 521-2
• Synonyms gene
  • MIRN521-2
• Synonyms
  • hsa-mir-521-2
• Locus
  19q13.42
• Discovery year
  2005-07-15
• Entrez gene record
  574481
• RefSeq identity
  • NR_030203
• Classification
  • MicroRNA MIR515 family

Gene info

• Identity
  HGNC:35282
• Gene
  MIR1289-2
• Long gene name
  microRNA 1289-2
• Synonyms gene
  • MIRN1289-2
• Synonyms
  • hsa-mir-1289-2
• Locus
  5q31.1
• Discovery year
  2008-11-03
• Entrez gene record
  100302134
• RefSeq identity
  • NR_031621
• Classification
  • MicroRNA MIR1289 family

Gene info

• Identity
  HGNC:33641
• Gene
  MIR509-2
• Long gene name
  microRNA 509-2
• Synonyms gene
  • MIRN509-2
• Synonyms
  • hsa-mir-509-2
• Locus
  Xq27.3
• Discovery year
  2007-10-24
• Entrez gene record
  100126301
• RefSeq identity
  • NR_030586
• Classification
  • MicroRNA MIR506 family

Gene info

• Identity
  HGNC:18923
• Gene
  KRTAP13-2
• Long gene name
  keratin associated protein 13-2
• Synonyms
  • KAP13-2
• GenBank acession
  • AP001708
• Locus
  21q22.11
• Discovery year
  2003-02-21
• Entrez gene record
  337959
• Pubmed identfication
  • 12359730
• Classification
  • Keratin associated proteins
• VEGA ID
  OTTHUMG00000057793

Gene info

• Identity
  HGNC:34270
• Gene
  RNU6-2
• Long gene name
  RNA, U6 small nuclear 2
• Synonyms
  • U6-2
• Locus
  19p13.3
• Discovery year
  2008-06-10
• Entrez gene record
  103625684
• Pubmed identfication
  • 12711679
• RefSeq identity
  • NR_125730
• Classification
  • Small nuclear RNAs

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