Angiotensin II Type 1 Receptor (AT1)

Products_type

Peptide
Products_short_name

[Angiotensin II Type 1 Receptor]
Other_names

[angiotensin II type 1 receptor]
Clonality

Polyclonal
Reactivity

Human, Mouse, Rat
Specificity

Recognizes rat Angiotensin II Receptor (AT1).
Purity

Affinity PurifiedPurified by immunoaffinity chromatography.
Form

Supplied as a liquid in PBS, pH 7.2, 0.01% sodium azide, 50% glycerol.
Storage_stability

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Tested_application

ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Description

The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

Identity

HGNC:95
Gene

SLC33A1
Long gene name

solute carrier family 33 member 1
Synonyms gene
- ACATN
- SPG42
Synonyms gene name
- acetyl-Coenzyme A transporter
- spastic paraplegia 42 (autosomal dominant)
- solute carrier family 33 (acetyl-CoA transporter), member 1
Synonyms
- AT-1
- AT1
GenBank acession
- D88152
Locus

3q25.31
Discovery year

1999-02-12
Entrez gene record

9197
Pubmed identfication
- 9096318
- 19061983
RefSeq identity
- NM_004733
Classification
- Solute carriers
VEGA ID

OTTHUMG00000158481