Tumor Necrosis Factor-alpha

MeSH code information

• Name
  Tumor Necrosis Factor-alpha
• Concept
  Scope note: Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS.
• Tree numbers
  • D12.644.276.374.500.800
  • D12.644.276.374.750.626
  • D12.776.124.900
  • D12.776.395.930
  • D12.776.467.374.500.800
  • D12.776.467.374.750.626
  • D23.529.374.500.800
  • D23.529.374.750.626
• Qualifiers
  isolation & purification, immunology, pharmacokinetics, biosynthesis, physiology, therapeutic use, agonists, blood, cerebrospinal fluid, chemical synthesis, deficiency, chemistry, drug effects, urine, radiation effects, history, analysis, classification, economics, genetics, pharmacology, standards, administration & dosage, antagonists & inhibitors, supply & distribution, ultrastructure, poisoning, adverse effects, toxicity, metabolism