Aromatase

MeSH code information
  • Name
  • Concept
    Registry number:EC 1.14.14.1
    Scope note:An enzyme that catalyzes the desaturation (aromatization) of the ring A of C19 androgens and converts them to C18 estrogens. In this process, the 19-methyl is removed. This enzyme is membrane-bound, located in the endoplasmic reticulum of estrogen-producing cells of ovaries, placenta, testes, adipose, and brain tissues. Aromatase is encoded by the CYP19 gene, and functions in complex with NADPH-FERRIHEMOPROTEIN REDUCTASE in the cytochrome P-450 system.
  • Tree numbers
    • D08.244.453.489.500
    • D08.244.453.915.099
    • D08.811.682.690.708.170.447.500
    • D08.811.682.690.708.170.915.099
    • D12.776.422.220.453.489.500
    • D12.776.422.220.453.915.099
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